Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1769

Experiment: 7H9 with Pretomanid 0.213 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pretomanid 0.213 ug/mL
2,001,729	+		Rv1768	0.60	+0.7
2,001,781	+		Rv1768	0.63	-0.2
2,001,934	-		Rv1768	0.71	-0.2
2,001,936	-		Rv1768	0.71	-0.2
2,001,936	-		Rv1768	0.71	+0.5
2,002,079	-		Rv1768	0.79	-1.1
2,002,079	-		Rv1768	0.79	-0.5
2,002,079	-		Rv1768	0.79	+1.0
2,002,396	-				-0.2
2,002,396	-				-0.5
2,002,439	+				+1.1
2,002,439	+				-0.1
2,002,439	+				-0.6
2,002,440	-				+0.4
2,002,496	-				+0.5
2,002,547	+				-1.1
2,002,547	+				+0.1
2,002,547	+				+0.3
2,002,547	+				+1.1
2,002,614	+				+1.5
2,002,615	-				+0.2
2,002,702	-				-3.0
2,002,745	-				-0.5
2,002,885	+		Rv1769	0.21	+1.6
2,002,953	+		Rv1769	0.26	-0.2
2,003,244	+		Rv1769	0.50	-1.6
2,003,245	-		Rv1769	0.50	-0.7
2,003,506	-		Rv1769	0.71	-0.8
2,003,551	+		Rv1769	0.74	+1.1
2,003,602	+		Rv1769	0.78	-0.5
2,003,603	-		Rv1769	0.78	-0.1
2,003,603	-		Rv1769	0.78	+0.1
2,003,603	-		Rv1769	0.78	+0.2
2,003,603	-		Rv1769	0.78	-0.1
2,003,749	-				+0.5
2,003,821	+				-0.7
2,003,841	+				-0.6
2,003,842	-				-0.5
2,003,868	+				-0.6
2,004,133	+		Rv1770	0.20	-0.0
2,004,133	+		Rv1770	0.20	-0.1
2,004,368	+		Rv1770	0.38	-1.9
2,004,429	+		Rv1770	0.43	-0.1
2,004,430	-		Rv1770	0.43	+0.3
2,004,430	-		Rv1770	0.43	-0.5
2,004,430	-		Rv1770	0.43	+0.1
2,004,440	+		Rv1770	0.44	+0.3
2,004,440	+		Rv1770	0.44	+0.0
2,004,441	-		Rv1770	0.44	-0.2
2,004,769	+		Rv1770	0.69	+0.6
2,004,769	+		Rv1770	0.69	+0.4
2,004,770	-		Rv1770	0.69	-0.2
2,004,817	+		Rv1770	0.73	-0.3
2,004,817	+		Rv1770	0.73	+2.3
2,004,817	+		Rv1770	0.73	-0.9
2,004,817	+		Rv1770	0.73	+0.5
2,004,817	+		Rv1770	0.73	-1.0
2,004,817	+		Rv1770	0.73	+0.5
2,004,817	+		Rv1770	0.73	-2.3
2,004,818	-		Rv1770	0.73	-0.5
2,004,818	-		Rv1770	0.73	-0.5
2,004,818	-		Rv1770	0.73	-0.9
2,004,818	-		Rv1770	0.73	-0.6
2,004,818	-		Rv1770	0.73	-0.2
2,004,818	-		Rv1770	0.73	-0.3
2,004,818	-		Rv1770	0.73	-0.5
2,004,818	-		Rv1770	0.73	-0.2