Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1169c

Experiment: 7H9 with Pretomanid 0.213 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pretomanid 0.213 ug/mL
1,298,922	+		Rv1168c	0.15	+0.3
1,298,923	-		Rv1168c	0.15	-0.6
1,299,022	+		Rv1168c	0.25	-0.0
1,299,122	+		Rv1168c	0.34	+0.7
1,299,122	+		Rv1168c	0.34	-0.2
1,299,122	+		Rv1168c	0.34	+0.4
1,299,123	-		Rv1168c	0.34	-0.1
1,299,123	-		Rv1168c	0.34	-0.7
1,299,266	+		Rv1168c	0.48	-0.5
1,299,266	+		Rv1168c	0.48	-0.6
1,299,267	-		Rv1168c	0.48	-0.7
1,299,353	+		Rv1168c	0.57	-0.2
1,299,387	-		Rv1168c	0.60	-0.4
1,299,395	+		Rv1168c	0.61	+1.5
1,299,396	-		Rv1168c	0.61	+0.0
1,299,692	+		Rv1168c	0.89	+0.3
1,299,736	+				-0.5
1,299,737	-				+0.3
1,299,866	-		Rv1169c	0.15	+1.9
1,299,940	+		Rv1169c	0.39	-0.4
1,299,941	-		Rv1169c	0.39	+3.1
1,299,941	-		Rv1169c	0.39	+0.1
1,300,231	-				-0.1
1,300,293	-				-0.2
1,300,385	+				-0.6
1,300,385	+				-0.5
1,300,386	-				-0.7
1,300,503	-		Rv1170	0.22	-0.1
1,300,709	+		Rv1170	0.44	-0.5
1,300,710	-		Rv1170	0.45	+0.9
1,300,728	-		Rv1170	0.46	-0.2
1,301,120	+		Rv1170	0.89	-2.2
1,301,121	-		Rv1170	0.90	+1.5
1,301,121	-		Rv1170	0.90	+0.3