Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0953c

Experiment: 7H9 with Pretomanid 0.213 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pretomanid 0.213 ug/mL
1,064,067	-				-0.2
1,064,067	-				-0.2
1,064,067	-				-0.8
1,064,154	+				+0.9
1,064,155	-				+0.0
1,064,207	-		Rv0953c	0.11	-0.3
1,064,315	+		Rv0953c	0.24	+2.1
1,064,493	+		Rv0953c	0.45	-0.4
1,064,493	+		Rv0953c	0.45	+0.5
1,064,494	-		Rv0953c	0.45	+0.9
1,064,494	-		Rv0953c	0.45	-0.2
1,064,538	+		Rv0953c	0.50	-0.6
1,064,784	+		Rv0953c	0.79	-0.4
1,065,233	+		Rv0954	0.12	+0.7
1,065,234	-		Rv0954	0.12	-0.6
1,065,281	-		Rv0954	0.17	-0.8
1,065,440	+		Rv0954	0.34	+1.1
1,065,440	+		Rv0954	0.34	-0.5
1,065,646	+		Rv0954	0.57	+1.2
1,065,697	+		Rv0954	0.62	-0.4
1,065,698	-		Rv0954	0.63	-0.7