Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0914c

Experiment: 7H9 with Pretomanid 0.213 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pretomanid 0.213 ug/mL
1,017,789	-		Rv0913c	0.38	-0.4
1,017,824	+		Rv0913c	0.40	-0.0
1,018,523	+		Rv0913c	0.87	-0.8
1,019,023	-		Rv0914c	0.24	+0.1
1,019,133	+		Rv0914c	0.33	+1.5
1,019,134	-		Rv0914c	0.33	-0.1
1,019,253	+		Rv0914c	0.42	+0.1
1,019,478	+		Rv0914c	0.61	+0.3
1,019,514	-		Rv0914c	0.64	+0.5
1,019,514	-		Rv0914c	0.64	+0.9
1,019,514	-		Rv0914c	0.64	-0.6
1,019,514	-		Rv0914c	0.64	-0.3
1,019,606	+		Rv0914c	0.71	+0.4
1,019,875	+				+1.2
1,019,966	-				-0.2
1,019,971	+				-0.9
1,019,971	+				-0.3
1,019,977	-				-1.2
1,019,979	+				-0.1
1,019,979	+				-0.3
1,020,059	+				-0.1
1,020,093	+				-0.3
1,020,094	-				-0.0
1,020,103	+				-1.0
1,020,103	+				+0.3
1,020,103	+				+0.2
1,020,103	+				-1.3
1,020,349	+		Rv0915c	0.23	-0.2
1,020,479	+		Rv0915c	0.33	-0.3
1,020,481	+		Rv0915c	0.33	+1.0
1,020,481	+		Rv0915c	0.33	+0.3
1,020,482	-		Rv0915c	0.33	-0.2
1,020,554	+		Rv0915c	0.39	+0.9
1,020,554	+		Rv0915c	0.39	+1.8
1,020,554	+		Rv0915c	0.39	+0.9
1,020,869	+		Rv0915c	0.64	-0.4
1,020,870	-		Rv0915c	0.64	-2.2
1,020,870	-		Rv0915c	0.64	-0.6
1,020,870	-		Rv0915c	0.64	-0.1
1,020,875	+		Rv0915c	0.64	-0.9
1,020,876	-		Rv0915c	0.64	-0.5
1,020,911	+		Rv0915c	0.67	-0.4