Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0547c

Experiment: 7H9 with Pretomanid 0.213 ug/mL

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv0545c and Rv0546c are separated by 119 nucleotidesRv0546c and Rv0547c are separated by 62 nucleotidesRv0547c and Rv0548c are separated by 95 nucleotides Rv0545c: Rv0545c - Probable low-affinity inorganic phosphate transporter integral membrane protein PitA, at 636,210 to 637,463 Rv0545c Rv0546c: Rv0546c - Conserved protein, at 637,583 to 637,969 Rv0546c Rv0547c: Rv0547c - Possible oxidoreductase, at 638,032 to 638,916 Rv0547c Rv0548c: Rv0548c - Naphthoate synthase MenB (dihydroxynaphthoic acid synthetase) (DHNA synthetase), at 639,012 to 639,956 Rv0548c Position (kb) 638 639Strain fitness (log2 ratio) -1 0 1 2at 637.326 kb on + strand, within Rv0545cat 637.529 kb on - strandat 637.552 kb on - strandat 637.552 kb on - strandat 637.552 kb on - strandat 637.563 kb on - strandat 637.563 kb on - strandat 637.600 kb on + strandat 637.869 kb on + strand, within Rv0546cat 637.982 kb on - strandat 638.210 kb on + strand, within Rv0547cat 638.210 kb on + strand, within Rv0547cat 638.211 kb on - strand, within Rv0547cat 638.255 kb on + strand, within Rv0547cat 638.256 kb on - strand, within Rv0547cat 638.256 kb on - strand, within Rv0547cat 638.256 kb on - strand, within Rv0547cat 638.400 kb on + strand, within Rv0547cat 638.462 kb on + strand, within Rv0547cat 638.462 kb on + strand, within Rv0547cat 638.463 kb on - strand, within Rv0547cat 638.463 kb on - strand, within Rv0547cat 638.465 kb on + strand, within Rv0547cat 638.465 kb on + strand, within Rv0547cat 638.465 kb on + strand, within Rv0547cat 638.465 kb on + strand, within Rv0547cat 638.465 kb on + strand, within Rv0547cat 638.466 kb on - strand, within Rv0547cat 638.697 kb on + strand, within Rv0547cat 638.930 kb on - strandat 638.930 kb on - strandat 638.947 kb on - strandat 638.947 kb on - strandat 638.990 kb on - strandat 639.013 kb on + strandat 639.020 kb on - strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Pretomanid 0.213 ug/mL
remove
637,326 + Rv0545c 0.89 +0.9
637,529 - +2.0
637,552 - +0.5
637,552 - +0.3
637,552 - +0.5
637,563 - +0.5
637,563 - -0.4
637,600 + +0.4
637,869 + Rv0546c 0.74 +0.8
637,982 - +0.0
638,210 + Rv0547c 0.20 +0.4
638,210 + Rv0547c 0.20 +0.2
638,211 - Rv0547c 0.20 -0.9
638,255 + Rv0547c 0.25 +0.4
638,256 - Rv0547c 0.25 +1.0
638,256 - Rv0547c 0.25 -1.1
638,256 - Rv0547c 0.25 -0.7
638,400 + Rv0547c 0.42 +0.5
638,462 + Rv0547c 0.49 +0.2
638,462 + Rv0547c 0.49 -0.4
638,463 - Rv0547c 0.49 -0.5
638,463 - Rv0547c 0.49 +0.1
638,465 + Rv0547c 0.49 +0.2
638,465 + Rv0547c 0.49 +1.2
638,465 + Rv0547c 0.49 -0.1
638,465 + Rv0547c 0.49 -0.2
638,465 + Rv0547c 0.49 -0.3
638,466 - Rv0547c 0.49 +0.2
638,697 + Rv0547c 0.75 +0.8
638,930 - +0.2
638,930 - -0.1
638,947 - -1.3
638,947 - -0.4
638,990 - -0.3
639,013 + -0.2
639,020 - +0.3

Or see this region's nucleotide sequence