Experiment: 7H9 with Pretomanid 0.213 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0371c and Rv0372c overlap by 4 nucleotides Rv0372c and Rv0373c are separated by 18 nucleotides Rv0373c and Rv0374c overlap by 4 nucleotides Rv0374c and Rv0375c are separated by 14 nucleotides
Rv0371c: Rv0371c - Conserved hypothetical protein, at 448,040 to 448,633
Rv0371c
Rv0372c: Rv0372c - Conserved hypothetical protein, at 448,630 to 449,385
Rv0372c
Rv0373c: Rv0373c - Probable carbon monoxyde dehydrogenase (large chain), at 449,404 to 451,803
Rv0373c
Rv0374c: Rv0374c - Probable carbon monoxyde dehydrogenase (small chain), at 451,800 to 452,279
Rv0374c
Rv0375c: Rv0375c - Probable carbon monoxyde dehydrogenase (medium chain), at 452,294 to 453,154
Rv0375c
Position (kb) 449
450
451
452 Strain fitness (log2 ratio) -1
0
1 at 449.405 kb on + strand at 449.646 kb on - strand, within Rv0373c at 449.862 kb on - strand, within Rv0373c at 449.867 kb on + strand, within Rv0373c at 449.868 kb on - strand, within Rv0373c at 450.140 kb on + strand, within Rv0373c at 450.141 kb on - strand, within Rv0373c at 450.720 kb on - strand, within Rv0373c at 450.738 kb on - strand, within Rv0373c at 450.884 kb on + strand, within Rv0373c at 450.983 kb on + strand, within Rv0373c at 451.199 kb on + strand, within Rv0373c at 451.492 kb on + strand, within Rv0373c at 451.492 kb on + strand, within Rv0373c at 451.864 kb on + strand, within Rv0374c at 451.955 kb on + strand, within Rv0374c at 452.386 kb on - strand, within Rv0375c at 452.386 kb on - strand, within Rv0375c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Pretomanid 0.213 ug/mL remove 449,405 + -0.2 449,646 - Rv0373c 0.10 -0.5 449,862 - Rv0373c 0.19 -0.9 449,867 + Rv0373c 0.19 -0.6 449,868 - Rv0373c 0.19 -0.7 450,140 + Rv0373c 0.31 +0.5 450,141 - Rv0373c 0.31 -0.1 450,720 - Rv0373c 0.55 -0.0 450,738 - Rv0373c 0.56 -0.3 450,884 + Rv0373c 0.62 -0.1 450,983 + Rv0373c 0.66 -1.3 451,199 + Rv0373c 0.75 -0.1 451,492 + Rv0373c 0.87 -0.2 451,492 + Rv0373c 0.87 -0.1 451,864 + Rv0374c 0.13 +0.2 451,955 + Rv0374c 0.32 -0.2 452,386 - Rv0375c 0.11 -0.3 452,386 - Rv0375c 0.11 -0.9
Or see this region's nucleotide sequence