Experiment: 7H9 with Pretomanid 0.213 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0244c and Rv0245 are separated by 371 nucleotides Rv0245 and Rv0246 are separated by 315 nucleotides
Rv0244c: Rv0244c - Probable acyl-CoA dehydrogenase FadE5, at 293,798 to 295,633
Rv0244c
Rv0245: Rv0245 - Possible oxidoreductase, at 296,005 to 296,493
Rv0245
Rv0246: Rv0246 - Probable conserved integral membrane protein, at 296,809 to 298,119
Rv0246
Position (kb) 296
297 Strain fitness (log2 ratio) -3
-2
-1
0
1 at 295.723 kb on + strand at 295.723 kb on + strand at 295.736 kb on + strand at 295.737 kb on - strand at 295.737 kb on - strand at 295.762 kb on - strand at 295.780 kb on - strand at 295.780 kb on - strand at 295.856 kb on + strand at 295.856 kb on + strand at 295.857 kb on - strand at 295.890 kb on + strand at 295.890 kb on + strand at 295.890 kb on + strand at 295.890 kb on + strand at 295.890 kb on + strand at 295.891 kb on - strand at 295.891 kb on - strand at 295.891 kb on - strand at 295.924 kb on + strand at 295.953 kb on + strand at 295.953 kb on + strand at 295.953 kb on + strand at 295.973 kb on - strand at 295.973 kb on - strand at 295.973 kb on - strand at 296.125 kb on - strand, within Rv0245 at 296.125 kb on - strand, within Rv0245 at 296.411 kb on + strand, within Rv0245 at 296.445 kb on - strand at 296.491 kb on + strand at 296.492 kb on - strand at 296.499 kb on + strand at 296.502 kb on - strand at 296.573 kb on - strand at 296.573 kb on - strand at 296.573 kb on - strand at 296.626 kb on - strand at 296.686 kb on + strand at 297.155 kb on + strand, within Rv0246 at 297.155 kb on + strand, within Rv0246 at 297.231 kb on + strand, within Rv0246 at 297.268 kb on - strand, within Rv0246 at 297.268 kb on - strand, within Rv0246 at 297.362 kb on + strand, within Rv0246 at 297.362 kb on + strand, within Rv0246 at 297.362 kb on + strand, within Rv0246 at 297.363 kb on - strand, within Rv0246 at 297.363 kb on - strand, within Rv0246 at 297.390 kb on + strand, within Rv0246 at 297.391 kb on - strand, within Rv0246 at 297.404 kb on + strand, within Rv0246 at 297.473 kb on - strand, within Rv0246 at 297.473 kb on - strand, within Rv0246
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Pretomanid 0.213 ug/mL remove 295,723 + -0.6 295,723 + +0.6 295,736 + +0.2 295,737 - +0.1 295,737 - -0.7 295,762 - +0.1 295,780 - -0.7 295,780 - -3.1 295,856 + -0.4 295,856 + -0.3 295,857 - -0.4 295,890 + -0.1 295,890 + -1.3 295,890 + -0.3 295,890 + +0.4 295,890 + +0.1 295,891 - +0.2 295,891 - -1.6 295,891 - -0.7 295,924 + -0.0 295,953 + -0.1 295,953 + +0.6 295,953 + -0.1 295,973 - +0.0 295,973 - -1.2 295,973 - -0.4 296,125 - Rv0245 0.25 -2.3 296,125 - Rv0245 0.25 -0.3 296,411 + Rv0245 0.83 -0.4 296,445 - -0.7 296,491 + -0.1 296,492 - +0.0 296,499 + -0.2 296,502 - +0.3 296,573 - -0.2 296,573 - -0.5 296,573 - +0.3 296,626 - -1.3 296,686 + -0.1 297,155 + Rv0246 0.26 +1.3 297,155 + Rv0246 0.26 -1.6 297,231 + Rv0246 0.32 +0.4 297,268 - Rv0246 0.35 -0.5 297,268 - Rv0246 0.35 +0.1 297,362 + Rv0246 0.42 +0.6 297,362 + Rv0246 0.42 -0.6 297,362 + Rv0246 0.42 +0.0 297,363 - Rv0246 0.42 +0.1 297,363 - Rv0246 0.42 -0.5 297,390 + Rv0246 0.44 -0.7 297,391 - Rv0246 0.44 +0.3 297,404 + Rv0246 0.45 -1.7 297,473 - Rv0246 0.51 +0.1 297,473 - Rv0246 0.51 +0.4
Or see this region's nucleotide sequence