Experiment: 7H9 with Pretomanid 0.213 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0143c and Rv0144 are separated by 101 nucleotides Rv0144 and Rv0145 are separated by 88 nucleotides
Rv0143c: Rv0143c - Probable conserved transmembrane protein, at 168,704 to 170,182
Rv0143c
Rv0144: Rv0144 - Probable transcriptional regulatory protein (possibly TetR-family), at 170,284 to 171,126
Rv0144
Rv0145: Rv0145 - Possible S-adenosylmethionine-dependent methyltransferase, at 171,215 to 172,168
Rv0145
Position (kb) 170
171
172 Strain fitness (log2 ratio) -2
-1
0
1 at 169.305 kb on + strand, within Rv0143c at 169.305 kb on + strand, within Rv0143c at 169.305 kb on + strand, within Rv0143c at 169.305 kb on + strand, within Rv0143c at 169.306 kb on - strand, within Rv0143c at 169.306 kb on - strand, within Rv0143c at 169.311 kb on + strand, within Rv0143c at 169.311 kb on + strand, within Rv0143c at 169.311 kb on + strand, within Rv0143c at 169.312 kb on - strand, within Rv0143c at 169.355 kb on + strand, within Rv0143c at 169.355 kb on + strand, within Rv0143c at 169.380 kb on + strand, within Rv0143c at 169.380 kb on + strand, within Rv0143c at 169.395 kb on + strand, within Rv0143c at 169.483 kb on - strand, within Rv0143c at 169.568 kb on + strand, within Rv0143c at 169.971 kb on + strand, within Rv0143c at 169.972 kb on - strand, within Rv0143c at 169.972 kb on - strand, within Rv0143c at 170.033 kb on + strand, within Rv0143c at 170.244 kb on - strand at 170.432 kb on + strand, within Rv0144 at 170.432 kb on + strand, within Rv0144 at 170.432 kb on + strand, within Rv0144 at 170.450 kb on + strand, within Rv0144 at 170.450 kb on + strand, within Rv0144 at 170.451 kb on - strand, within Rv0144 at 170.451 kb on - strand, within Rv0144 at 170.454 kb on + strand, within Rv0144 at 170.454 kb on + strand, within Rv0144 at 170.480 kb on + strand, within Rv0144 at 170.480 kb on + strand, within Rv0144 at 170.481 kb on - strand, within Rv0144 at 170.481 kb on - strand, within Rv0144 at 170.559 kb on + strand, within Rv0144 at 170.560 kb on - strand, within Rv0144 at 170.560 kb on - strand, within Rv0144 at 170.665 kb on + strand, within Rv0144 at 170.665 kb on + strand, within Rv0144 at 170.666 kb on - strand, within Rv0144 at 170.689 kb on + strand, within Rv0144 at 170.689 kb on + strand, within Rv0144 at 170.689 kb on + strand, within Rv0144 at 170.689 kb on + strand, within Rv0144 at 171.031 kb on + strand, within Rv0144 at 171.031 kb on + strand, within Rv0144 at 171.032 kb on - strand, within Rv0144 at 171.032 kb on - strand, within Rv0144 at 171.032 kb on - strand, within Rv0144 at 171.032 kb on - strand, within Rv0144 at 171.033 kb on + strand, within Rv0144 at 171.052 kb on + strand at 171.052 kb on + strand at 171.052 kb on + strand at 171.201 kb on + strand at 171.202 kb on - strand at 171.202 kb on - strand at 171.489 kb on - strand, within Rv0145 at 171.521 kb on + strand, within Rv0145 at 171.657 kb on - strand, within Rv0145 at 171.657 kb on - strand, within Rv0145 at 171.753 kb on + strand, within Rv0145 at 171.753 kb on + strand, within Rv0145 at 171.808 kb on - strand, within Rv0145 at 171.958 kb on - strand, within Rv0145 at 171.984 kb on - strand, within Rv0145
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Pretomanid 0.213 ug/mL remove 169,305 + Rv0143c 0.41 -0.1 169,305 + Rv0143c 0.41 -0.4 169,305 + Rv0143c 0.41 -0.7 169,305 + Rv0143c 0.41 -0.5 169,306 - Rv0143c 0.41 +0.4 169,306 - Rv0143c 0.41 -0.1 169,311 + Rv0143c 0.41 -1.3 169,311 + Rv0143c 0.41 +0.0 169,311 + Rv0143c 0.41 +0.2 169,312 - Rv0143c 0.41 -1.5 169,355 + Rv0143c 0.44 -0.6 169,355 + Rv0143c 0.44 -0.6 169,380 + Rv0143c 0.46 -1.0 169,380 + Rv0143c 0.46 -0.2 169,395 + Rv0143c 0.47 +1.1 169,483 - Rv0143c 0.53 -0.1 169,568 + Rv0143c 0.58 -0.4 169,971 + Rv0143c 0.86 -0.6 169,972 - Rv0143c 0.86 -0.2 169,972 - Rv0143c 0.86 -0.3 170,033 + Rv0143c 0.90 -1.2 170,244 - -0.4 170,432 + Rv0144 0.18 -0.0 170,432 + Rv0144 0.18 -1.0 170,432 + Rv0144 0.18 +1.5 170,450 + Rv0144 0.20 -0.9 170,450 + Rv0144 0.20 -0.5 170,451 - Rv0144 0.20 +1.6 170,451 - Rv0144 0.20 +0.2 170,454 + Rv0144 0.20 -0.6 170,454 + Rv0144 0.20 -0.7 170,480 + Rv0144 0.23 -0.5 170,480 + Rv0144 0.23 -0.3 170,481 - Rv0144 0.23 -0.0 170,481 - Rv0144 0.23 -0.8 170,559 + Rv0144 0.33 -0.2 170,560 - Rv0144 0.33 -0.8 170,560 - Rv0144 0.33 -1.5 170,665 + Rv0144 0.45 -0.4 170,665 + Rv0144 0.45 -1.0 170,666 - Rv0144 0.45 -0.5 170,689 + Rv0144 0.48 +0.3 170,689 + Rv0144 0.48 +0.0 170,689 + Rv0144 0.48 +0.2 170,689 + Rv0144 0.48 -0.8 171,031 + Rv0144 0.89 -0.4 171,031 + Rv0144 0.89 +0.4 171,032 - Rv0144 0.89 -0.0 171,032 - Rv0144 0.89 +0.2 171,032 - Rv0144 0.89 -0.2 171,032 - Rv0144 0.89 -0.3 171,033 + Rv0144 0.89 -2.3 171,052 + +0.4 171,052 + +0.0 171,052 + +0.0 171,201 + -2.0 171,202 - -0.1 171,202 - -0.0 171,489 - Rv0145 0.29 -1.8 171,521 + Rv0145 0.32 -1.6 171,657 - Rv0145 0.46 -0.8 171,657 - Rv0145 0.46 -0.4 171,753 + Rv0145 0.56 -1.3 171,753 + Rv0145 0.56 -0.3 171,808 - Rv0145 0.62 -1.3 171,958 - Rv0145 0.78 -0.2 171,984 - Rv0145 0.81 -0.9
Or see this region's nucleotide sequence