Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0615

Experiment: 7H9 with para-aminosalicylic 0.086 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0613c and Rv0614 overlap by 160 nucleotidesRv0614 and Rv0615 overlap by 4 nucleotidesRv0615 and Rv0616c overlap by 4 nucleotidesRv0616c and Rv0616A overlap by 69 nucleotidesRv0616A and Rv0617 overlap by 4 nucleotidesRv0617 and Rv0618 are separated by 128 nucleotides Rv0613c: Rv0613c - Unknown protein, at 706,948 to 709,515 Rv0613c Rv0614: Rv0614 - Conserved hypothetical protein, at 709,356 to 710,348 Rv0614 Rv0615: Rv0615 - Probable integral membrane protein, at 710,345 to 710,587 Rv0615 Rv0616c: Rv0616c - Hypothetical protein, at 710,584 to 710,850 Rv0616c Rv0616A: Rv0616A - Possible antitoxin VapB29, at 710,782 to 711,009 Rv0616A Rv0617: Rv0617 - Possible toxin VapC29. Contains PIN domain., at 711,006 to 711,407 Rv0617 Rv0618: Rv0618 - Probable galactose-1-phosphate uridylyltransferase GalTa [first part], at 711,536 to 712,231 Rv0618 Position (kb) 710 711Strain fitness (log2 ratio) -2 -1 0 1 2at 709.527 kb on + strand, within Rv0614at 709.527 kb on + strand, within Rv0614at 709.527 kb on + strand, within Rv0614at 709.527 kb on + strand, within Rv0614at 709.528 kb on - strand, within Rv0614at 709.750 kb on + strand, within Rv0614at 709.751 kb on - strand, within Rv0614at 709.991 kb on + strand, within Rv0614at 710.028 kb on - strand, within Rv0614at 710.071 kb on + strand, within Rv0614at 710.072 kb on - strand, within Rv0614at 710.157 kb on + strand, within Rv0614at 710.323 kb on + strandat 710.323 kb on + strandat 710.355 kb on + strandat 710.355 kb on + strandat 710.435 kb on + strand, within Rv0615at 710.436 kb on - strand, within Rv0615at 710.586 kb on - strandat 710.790 kb on + strandat 710.790 kb on + strandat 710.993 kb on + strandat 711.300 kb on + strand, within Rv0617at 711.301 kb on - strand, within Rv0617at 711.301 kb on - strand, within Rv0617at 711.470 kb on + strandat 711.476 kb on + strandat 711.477 kb on - strandat 711.477 kb on - strandat 711.477 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with para-aminosalicylic 0.086 ug/mL
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709,527 + Rv0614 0.17 -0.2
709,527 + Rv0614 0.17 -0.1
709,527 + Rv0614 0.17 +0.1
709,527 + Rv0614 0.17 -0.7
709,528 - Rv0614 0.17 +0.8
709,750 + Rv0614 0.40 +0.2
709,751 - Rv0614 0.40 -0.1
709,991 + Rv0614 0.64 +0.4
710,028 - Rv0614 0.68 +2.5
710,071 + Rv0614 0.72 +0.8
710,072 - Rv0614 0.72 +0.5
710,157 + Rv0614 0.81 +1.4
710,323 + +1.2
710,323 + +0.0
710,355 + -0.1
710,355 + -0.2
710,435 + Rv0615 0.37 -2.3
710,436 - Rv0615 0.37 -0.7
710,586 - -0.4
710,790 + -1.0
710,790 + +0.2
710,993 + +0.2
711,300 + Rv0617 0.73 -0.5
711,301 - Rv0617 0.73 -0.3
711,301 - Rv0617 0.73 +0.4
711,470 + -0.2
711,476 + -0.0
711,477 - -0.7
711,477 - -0.6
711,477 - +0.4

Or see this region's nucleotide sequence