Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3577

Experiment: 7H9 with Meropenem 9.6 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Meropenem 9.6 ug/mL
4,018,322	+				-0.6
4,018,322	+				-0.7
4,018,323	-				-2.0
4,018,787	+		Rv3576	0.60	+1.1
4,018,788	-		Rv3576	0.60	-0.3
4,018,909	+		Rv3576	0.77	+0.2
4,018,982	-		Rv3576	0.87	-0.3
4,019,006	-				+0.2
4,019,117	+				+0.0
4,019,117	+				-0.6
4,019,258	+				+0.0
4,019,863	-		Rv3577	0.69	-0.8
4,019,901	+		Rv3577	0.74	-0.0
4,019,902	-		Rv3577	0.74	-0.5
4,019,902	-		Rv3577	0.74	-0.1
4,019,902	-		Rv3577	0.74	+0.2
4,020,032	-		Rv3577	0.89	-0.5
4,020,032	-		Rv3577	0.89	+0.2
4,020,136	+				+0.1
4,020,556	+		Rv3578	0.33	-0.2
4,020,557	-		Rv3578	0.33	-1.5
4,020,628	+		Rv3578	0.39	-0.4
4,020,628	+		Rv3578	0.39	+0.2
4,020,706	+		Rv3578	0.45	-0.1
4,020,706	+		Rv3578	0.45	+0.2
4,020,707	-		Rv3578	0.45	+0.3
4,020,740	+		Rv3578	0.48	-1.2