Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3544c

Experiment: 7H9 with Meropenem 9.6 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Meropenem 9.6 ug/mL
3,982,134	+		Rv3543c	0.13	+0.1
3,982,377	+		Rv3543c	0.34	-0.9
3,982,378	-		Rv3543c	0.34	+0.2
3,982,506	+		Rv3543c	0.45	-0.2
3,983,019	+		Rv3543c	0.90	+0.3
3,983,211	-				-0.8
3,983,214	-				+0.6
3,983,403	-		Rv3544c	0.27	+0.1
3,983,403	-		Rv3544c	0.27	-1.1
3,983,477	+		Rv3544c	0.35	-0.0
3,983,523	-		Rv3544c	0.39	+0.8
3,983,523	-		Rv3544c	0.39	-0.4
3,983,652	+		Rv3544c	0.52	-2.9
3,983,653	-		Rv3544c	0.52	-0.6
3,983,995	+		Rv3544c	0.85	-0.8
3,984,146	-				+0.8
3,984,164	+				+0.3
3,984,165	-				-1.0
3,984,172	+				-0.3
3,984,173	-				-0.4
3,984,191	+				-0.4
3,984,279	+		Rv3545c	0.10	-2.3
3,984,280	-		Rv3545c	0.10	+0.3
3,984,319	+		Rv3545c	0.13	+1.0
3,984,320	-		Rv3545c	0.14	-0.2
3,984,374	+		Rv3545c	0.18	-0.3
3,984,374	+		Rv3545c	0.18	-0.6
3,984,375	-		Rv3545c	0.18	+0.2
3,984,452	+		Rv3545c	0.24	-1.2
3,984,452	+		Rv3545c	0.24	-1.1
3,984,565	+		Rv3545c	0.32	-0.4
3,984,565	+		Rv3545c	0.32	-0.2
3,984,565	+		Rv3545c	0.32	-1.0
3,984,566	-		Rv3545c	0.32	+0.5
3,984,823	+		Rv3545c	0.52	-0.3
3,984,823	+		Rv3545c	0.52	-0.8