Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3389c

Experiment: 7H9 with Meropenem 9.6 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Meropenem 9.6 ug/mL
3,803,262	+		Rv3388	0.73	+0.0
3,803,262	+		Rv3388	0.73	+0.7
3,803,262	+		Rv3388	0.73	+0.3
3,803,846	+				+1.4
3,803,846	+				-0.3
3,803,846	+				-1.1
3,803,846	+				-0.1
3,803,847	-				+0.6
3,803,847	-				+0.4
3,803,847	-				+0.0
3,803,847	-				+0.1
3,803,847	-				-0.0
3,803,932	+				-1.1
3,803,932	+				-0.6
3,803,932	+				-0.3
3,803,933	-				+0.3
3,803,933	-				+0.1
3,804,151	+		Rv3389c	0.27	-0.1
3,804,281	+		Rv3389c	0.41	+1.1
3,804,282	-		Rv3389c	0.42	+0.5
3,804,555	+		Rv3389c	0.73	-0.5
3,804,556	-		Rv3389c	0.73	+1.2
3,804,768	+				-0.3
3,804,768	+				+0.0
3,804,769	-				-0.9
3,804,769	-				-1.4
3,804,769	-				+0.2
3,804,858	+				-0.0
3,804,905	+				+0.4
3,804,906	-				-0.2
3,804,906	-				+0.2
3,804,927	-				-0.0
3,804,927	-				-0.4
3,804,981	+		Rv3390	0.16	-0.3
3,805,120	+		Rv3390	0.36	-1.5
3,805,120	+		Rv3390	0.36	-0.0
3,805,120	+		Rv3390	0.36	+0.0
3,805,120	+		Rv3390	0.36	-1.7
3,805,120	+		Rv3390	0.36	-0.9
3,805,120	+		Rv3390	0.36	+0.9
3,805,121	-		Rv3390	0.36	+1.8
3,805,121	-		Rv3390	0.36	+0.2
3,805,121	-		Rv3390	0.36	+1.5
3,805,121	-		Rv3390	0.36	-1.5
3,805,264	+		Rv3390	0.56	-1.0
3,805,264	+		Rv3390	0.56	-0.4
3,805,265	-		Rv3390	0.56	+1.0
3,805,265	-		Rv3390	0.56	+1.8
3,805,265	-		Rv3390	0.56	+0.4
3,805,266	+		Rv3390	0.56	-0.2
3,805,266	+		Rv3390	0.56	+0.2
3,805,266	+		Rv3390	0.56	-0.3
3,805,267	-		Rv3390	0.57	-1.1
3,805,267	-		Rv3390	0.57	+0.1
3,805,267	-		Rv3390	0.57	-0.1
3,805,267	-		Rv3390	0.57	+0.3
3,805,311	+		Rv3390	0.63	-0.3
3,805,311	+		Rv3390	0.63	-0.3
3,805,312	-		Rv3390	0.63	-0.4
3,805,312	-		Rv3390	0.63	-1.6
3,805,312	-		Rv3390	0.63	-0.5
3,805,375	+		Rv3390	0.72	+1.8
3,805,376	-		Rv3390	0.72	+0.0
3,805,376	-		Rv3390	0.72	-0.4
3,805,376	-		Rv3390	0.72	-1.0
3,805,392	+		Rv3390	0.74	+0.4
3,805,392	+		Rv3390	0.74	-0.5
3,805,670	+				-0.3
3,805,671	-				+0.5