Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3229c

Experiment: 7H9 with Meropenem 9.6 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3228 and Rv3229c are separated by 32 nucleotidesRv3229c and Rv3230c are separated by 77 nucleotides Rv3228: Rv3228 - Conserved hypothetical protein, at 3,604,726 to 3,605,718 Rv3228 Rv3229c: Rv3229c - Possible linoleoyl-CoA desaturase (delta(6)-desaturase), at 3,605,751 to 3,607,034 Rv3229c Rv3230c: Rv3230c - Hypothetical oxidoreductase, at 3,607,112 to 3,608,254 Rv3230c Position (kb) 3605 3606 3607 3608Strain fitness (log2 ratio) -2 -1 0 1at 3605.786 kb on + strandat 3605.786 kb on + strandat 3605.787 kb on - strandat 3605.787 kb on - strandat 3605.787 kb on - strandat 3605.793 kb on - strandat 3605.951 kb on - strand, within Rv3229cat 3606.389 kb on - strand, within Rv3229cat 3606.640 kb on + strand, within Rv3229cat 3606.641 kb on - strand, within Rv3229cat 3606.641 kb on - strand, within Rv3229cat 3606.911 kb on - strandat 3606.964 kb on - strandat 3607.068 kb on - strandat 3607.073 kb on - strandat 3607.113 kb on + strandat 3607.268 kb on + strand, within Rv3230cat 3607.269 kb on - strand, within Rv3230cat 3607.269 kb on - strand, within Rv3230cat 3607.659 kb on - strand, within Rv3230cat 3607.714 kb on + strand, within Rv3230cat 3607.714 kb on + strand, within Rv3230cat 3607.971 kb on + strand, within Rv3230cat 3607.972 kb on - strand, within Rv3230cat 3607.972 kb on - strand, within Rv3230c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Meropenem 9.6 ug/mL
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3,605,786 + -0.8
3,605,786 + -0.6
3,605,787 - -0.4
3,605,787 - +0.0
3,605,787 - +0.0
3,605,793 - +0.0
3,605,951 - Rv3229c 0.16 -1.0
3,606,389 - Rv3229c 0.50 +0.7
3,606,640 + Rv3229c 0.69 +0.3
3,606,641 - Rv3229c 0.69 -1.9
3,606,641 - Rv3229c 0.69 +0.6
3,606,911 - +1.1
3,606,964 - +0.6
3,607,068 - -0.4
3,607,073 - -0.8
3,607,113 + +0.7
3,607,268 + Rv3230c 0.14 +0.9
3,607,269 - Rv3230c 0.14 +0.8
3,607,269 - Rv3230c 0.14 +0.8
3,607,659 - Rv3230c 0.48 -0.0
3,607,714 + Rv3230c 0.53 +0.9
3,607,714 + Rv3230c 0.53 +1.4
3,607,971 + Rv3230c 0.75 +0.9
3,607,972 - Rv3230c 0.75 +0.8
3,607,972 - Rv3230c 0.75 +1.0

Or see this region's nucleotide sequence