Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3220c

Experiment: 7H9 with Meropenem 9.6 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Meropenem 9.6 ug/mL
3,595,043	+		Rv3218	0.60	+0.3
3,595,043	+		Rv3218	0.60	-0.5
3,595,043	+		Rv3218	0.60	-0.1
3,595,043	+		Rv3218	0.60	-1.0
3,595,044	-		Rv3218	0.60	-0.4
3,595,120	-		Rv3218	0.67	-0.4
3,595,298	-		Rv3218	0.86	-0.7
3,595,498	+				+1.4
3,595,501	+				-0.7
3,595,501	+				+1.8
3,596,000	-				-0.7
3,596,000	-				-0.4
3,596,106	+				+0.4
3,596,796	+		Rv3220c	0.51	+2.5
3,596,796	+		Rv3220c	0.51	+1.0
3,596,961	-		Rv3220c	0.62	+1.1
3,597,301	-		Rv3220c	0.84	+0.7
3,597,416	+				+1.1
3,597,552	+				-0.5
3,597,838	-				+0.8
3,597,838	-				+0.2
3,597,838	-				-2.4
3,597,847	+				-1.1
3,597,847	+				-2.2
3,597,848	-				+0.6
3,597,848	-				+0.6
3,597,848	-				+0.3
3,597,877	+				-2.2
3,597,985	-				-0.0
3,598,003	+				-0.6
3,598,003	+				-0.7
3,598,003	+				-0.3
3,598,039	+				-1.2