Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3138

Experiment: 7H9 with Meropenem 9.6 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Meropenem 9.6 ug/mL
3,503,209	-		Rv3136A	0.79	+0.6
3,503,249	-				+0.4
3,503,288	+				+0.2
3,503,365	-				+0.2
3,504,265	+				-0.0
3,504,266	-				+0.1
3,504,266	-				+0.1
3,504,266	-				-1.5
3,504,489	-		Rv3138	0.27	-0.2
3,504,618	+		Rv3138	0.39	-0.3
3,504,619	-		Rv3138	0.39	-0.9
3,504,745	+		Rv3138	0.51	+0.4
3,504,746	-		Rv3138	0.51	-0.9
3,504,769	-		Rv3138	0.53	-0.4
3,504,819	+		Rv3138	0.57	-1.0
3,504,879	-		Rv3138	0.63	-1.0
3,505,158	+		Rv3138	0.88	-1.1
3,505,216	-				-0.1
3,505,216	-				-0.2
3,505,362	+				-0.2
3,505,363	-				-1.5
3,505,419	+				-1.5
3,505,528	+		Rv3139	0.12	-0.9
3,505,673	-		Rv3139	0.22	-2.3
3,505,784	-		Rv3139	0.30	-1.0
3,505,825	-		Rv3139	0.33	-1.7
3,505,825	-		Rv3139	0.33	-1.5
3,505,857	+		Rv3139	0.35	-2.0
3,505,913	-		Rv3139	0.39	+0.2
3,506,178	+		Rv3139	0.58	-1.0
3,506,179	-		Rv3139	0.58	-0.3