Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3136A

Experiment: 7H9 with Meropenem 9.6 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Meropenem 9.6 ug/mL
3,502,008	-		Rv3136	0.19	+0.7
3,502,010	-		Rv3136	0.19	+0.7
3,502,022	+		Rv3136	0.20	+0.5
3,502,094	+		Rv3136	0.26	-0.2
3,502,095	-		Rv3136	0.26	+1.1
3,502,212	-		Rv3136	0.37	+0.0
3,502,247	+		Rv3136	0.40	+0.8
3,502,247	+		Rv3136	0.40	+0.9
3,502,248	-		Rv3136	0.40	-0.0
3,502,254	-		Rv3136	0.40	+0.6
3,502,542	+		Rv3136	0.65	+0.8
3,502,542	+		Rv3136	0.65	-0.2
3,502,946	+				-0.0
3,502,971	+				-0.5
3,502,971	+				+0.5
3,502,972	-				+1.0
3,503,004	-		Rv3136A	0.18	+0.9
3,503,017	+		Rv3136A	0.22	+0.9
3,503,066	+		Rv3136A	0.36	+0.3
3,503,066	+		Rv3136A	0.36	+0.5
3,503,120	+		Rv3136A	0.53	+0.6
3,503,120	+		Rv3136A	0.53	+0.4
3,503,120	+		Rv3136A	0.53	+0.4
3,503,121	-		Rv3136A	0.53	+0.5
3,503,121	-		Rv3136A	0.53	-0.6
3,503,121	-		Rv3136A	0.53	+0.5
3,503,209	-		Rv3136A	0.79	+0.6
3,503,249	-				+0.4
3,503,288	+				+0.2
3,503,365	-				+0.2
3,504,265	+				-0.0
3,504,266	-				+0.1
3,504,266	-				+0.1
3,504,266	-				-1.5