Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2482c

Experiment: 7H9 with Meropenem 9.6 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Meropenem 9.6 ug/mL
2,786,004	+				+0.0
2,786,060	+				-0.2
2,786,073	-				-0.8
2,786,155	-				-1.3
2,786,163	-				-0.0
2,786,163	-				+0.4
2,786,214	+				+0.3
2,786,215	-				-0.1
2,786,292	+				+0.3
2,786,293	-				-0.2
2,786,359	+				-0.3
2,786,381	-				-0.4
2,786,385	-				-0.1
2,786,394	+				+0.2
2,786,394	+				+0.0
2,786,452	+				+0.3
2,786,452	+				+1.7
2,786,453	-				-1.2
2,786,453	-				+1.0
2,786,453	-				-0.2
2,786,576	+				+1.1
2,786,576	+				-0.5
2,786,576	+				-0.6
2,786,577	-				-0.6
2,786,584	+				-0.2
2,786,584	+				-0.6
2,786,585	-				-0.3
2,786,587	-				-0.4
2,786,602	-				-0.1
2,786,725	+		Rv2481c	0.46	-0.4
2,786,726	-		Rv2481c	0.47	+0.3
2,786,726	-		Rv2481c	0.47	-0.5
2,786,886	+				-0.0
2,786,915	+				-0.4
2,786,916	-				-1.1
2,787,014	-				-0.8
2,787,037	-				+0.8
2,787,037	-				-0.3
2,787,037	-				-0.4
2,787,037	-				-0.6
2,787,245	+		Rv2482c	0.14	+0.5
2,787,246	-		Rv2482c	0.14	+0.3
2,787,246	-		Rv2482c	0.14	-0.6
2,787,300	-		Rv2482c	0.16	+0.2
2,787,410	+		Rv2482c	0.21	-0.1
2,787,410	+		Rv2482c	0.21	-0.1
2,787,410	+		Rv2482c	0.21	+1.5
2,787,411	-		Rv2482c	0.21	-0.2
2,787,411	-		Rv2482c	0.21	-0.7
2,787,555	-		Rv2482c	0.27	-0.8
2,787,587	-		Rv2482c	0.28	-0.3
2,787,587	-		Rv2482c	0.28	-0.0
2,787,590	+		Rv2482c	0.29	-1.1
2,787,591	-		Rv2482c	0.29	-0.1
2,787,971	+		Rv2482c	0.45	-0.3
2,788,017	-		Rv2482c	0.47	-0.5
2,788,164	-		Rv2482c	0.53	+0.6
2,788,284	-		Rv2482c	0.58	+0.3
2,788,287	+		Rv2482c	0.58	+0.1
2,788,289	+		Rv2482c	0.58	+0.3
2,788,517	+		Rv2482c	0.68	-0.5
2,788,727	+		Rv2482c	0.76	+0.0
2,789,028	+		Rv2482c	0.89	+0.3
2,789,028	+		Rv2482c	0.89	-0.1
2,789,029	-		Rv2482c	0.89	+0.9
2,789,513	-		Rv2483c	0.13	-0.3
2,789,566	+		Rv2483c	0.16	-0.7
2,789,751	-		Rv2483c	0.27	+1.8
2,789,790	-		Rv2483c	0.29	-1.1