Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2453c

Experiment: 7H9 with Meropenem 9.6 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Meropenem 9.6 ug/mL
2,752,233	+				-0.3
2,752,390	-		Rv2451	0.32	-0.1
2,752,447	+		Rv2451	0.46	-0.6
2,752,479	+		Rv2451	0.54	-0.3
2,752,483	+		Rv2451	0.55	-0.2
2,752,563	+		Rv2451	0.75	-0.1
2,752,563	+		Rv2451	0.75	+0.8
2,752,563	+		Rv2451	0.75	-0.0
2,752,564	-		Rv2451	0.76	-0.1
2,752,744	+				+0.7
2,752,760	+				+0.0
2,752,760	+				-0.1
2,752,761	-				-0.1
2,752,782	-				-0.4
2,752,805	+				-0.8
2,752,922	+		Rv2452c	0.50	-0.1
2,752,947	+		Rv2452c	0.67	-0.4
2,752,947	+		Rv2452c	0.67	-0.1
2,753,013	+				-0.5
2,753,190	+		Rv2453c	0.28	+0.2
2,753,205	+		Rv2453c	0.31	-0.6
2,753,206	-		Rv2453c	0.31	-0.3
2,753,494	+		Rv2453c	0.79	-1.4
2,753,494	+		Rv2453c	0.79	+0.3
2,753,494	+		Rv2453c	0.79	-0.1
2,753,495	-		Rv2453c	0.79	-0.3
2,753,495	-		Rv2453c	0.79	-0.2
2,753,495	-		Rv2453c	0.79	-0.6
2,753,495	-		Rv2453c	0.79	+0.0
2,753,495	-		Rv2453c	0.79	-1.7
2,753,495	-		Rv2453c	0.79	-0.3