Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2382c

Experiment: 7H9 with Meropenem 9.6 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2381c and Rv2382c overlap by 1 nucleotidesRv2382c and Rv2383c overlap by 11 nucleotides Rv2381c: Rv2381c - Polyketide synthetase MbtD (polyketide synthase), at 2,667,255 to 2,670,269 Rv2381c Rv2382c: Rv2382c - Polyketide synthetase MbtC (polyketide synthase), at 2,670,269 to 2,671,603 Rv2382c Rv2383c: Rv2383c - Phenyloxazoline synthase MbtB (phenyloxazoline synthetase), at 2,671,593 to 2,675,837 Rv2383c Position (kb) 2670 2671 2672Strain fitness (log2 ratio) -1 0 1at 2669.660 kb on + strand, within Rv2381cat 2671.123 kb on - strand, within Rv2382cat 2671.301 kb on + strand, within Rv2382cat 2671.648 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Meropenem 9.6 ug/mL
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2,669,660 + Rv2381c 0.80 -0.8
2,671,123 - Rv2382c 0.64 +1.2
2,671,301 + Rv2382c 0.77 +0.0
2,671,648 + +0.6

Or see this region's nucleotide sequence