Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1999c

Experiment: 7H9 with Meropenem 9.6 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Meropenem 9.6 ug/mL
2,242,858	-				+0.2
2,243,001	-				-0.7
2,243,063	+		Rv1998c	0.15	-0.5
2,243,161	-		Rv1998c	0.28	-0.3
2,243,507	+		Rv1998c	0.72	-1.4
2,243,757	-				-0.1
2,243,757	-				-0.4
2,243,757	-				-0.1
2,243,757	-				+0.4
2,243,817	+				-0.9
2,244,069	+		Rv1999c	0.19	-0.6
2,244,213	-		Rv1999c	0.30	-0.3
2,244,426	+		Rv1999c	0.46	+0.1
2,244,426	+		Rv1999c	0.46	-0.0
2,244,427	-		Rv1999c	0.46	+0.4
2,244,715	-		Rv1999c	0.68	+0.9
2,244,891	+		Rv1999c	0.81	-0.3
2,244,891	+		Rv1999c	0.81	-0.8
2,244,891	+		Rv1999c	0.81	+0.3
2,244,892	-		Rv1999c	0.81	+0.1
2,244,892	-		Rv1999c	0.81	+0.5
2,244,892	-		Rv1999c	0.81	+0.8
2,244,892	-		Rv1999c	0.81	+1.0
2,244,892	-		Rv1999c	0.81	+0.5
2,244,892	-		Rv1999c	0.81	-0.2
2,244,892	-		Rv1999c	0.81	-0.0
2,245,254	+				-0.2
2,245,254	+				-0.1
2,245,448	-		Rv2000	0.15	-0.1
2,245,448	-		Rv2000	0.15	+1.3
2,245,593	+		Rv2000	0.24	-0.8
2,245,596	+		Rv2000	0.24	+0.9
2,245,596	+		Rv2000	0.24	-0.1
2,245,687	+		Rv2000	0.30	+0.2
2,245,687	+		Rv2000	0.30	-0.1
2,245,708	+		Rv2000	0.31	-0.8
2,245,709	-		Rv2000	0.31	-0.3
2,245,746	+		Rv2000	0.33	-0.2
2,245,764	+		Rv2000	0.34	-1.9
2,245,764	+		Rv2000	0.34	-0.3
2,245,806	+		Rv2000	0.37	+0.0
2,245,807	-		Rv2000	0.37	+0.2
2,245,845	+		Rv2000	0.39	-0.0
2,245,845	+		Rv2000	0.39	+0.2
2,245,845	+		Rv2000	0.39	-0.4
2,245,845	+		Rv2000	0.39	+0.2
2,245,846	-		Rv2000	0.39	-0.9
2,245,953	+		Rv2000	0.46	+0.1
2,245,954	-		Rv2000	0.46	-0.3
2,245,954	-		Rv2000	0.46	-0.3
2,245,996	+		Rv2000	0.49	-0.2
2,245,996	+		Rv2000	0.49	-0.3
2,245,997	-		Rv2000	0.49	-0.6
2,245,997	-		Rv2000	0.49	-1.1