Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1919c

Experiment: 7H9 with Meropenem 9.6 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Meropenem 9.6 ug/mL
2,170,153	-		Rv1918c	0.84	-0.4
2,170,169	+		Rv1918c	0.85	-2.1
2,170,170	-		Rv1918c	0.85	+1.2
2,170,194	+		Rv1918c	0.86	-0.0
2,170,259	+		Rv1918c	0.88	+0.1
2,170,260	-		Rv1918c	0.88	+0.8
2,170,299	-		Rv1918c	0.89	-0.4
2,170,605	+				-0.6
2,170,605	+				-0.0
2,170,606	-				+1.0
2,171,051	+				-1.6
2,171,222	+		Rv1919c	0.35	+1.4
2,171,222	+		Rv1919c	0.35	-0.4
2,171,222	+		Rv1919c	0.35	+1.2
2,171,222	+		Rv1919c	0.35	+1.0
2,171,278	+		Rv1919c	0.47	+0.1
2,171,279	-		Rv1919c	0.47	+0.3
2,171,344	-		Rv1919c	0.61	+1.1
2,171,344	-		Rv1919c	0.61	+0.9
2,171,561	+				-0.1
2,171,576	+				-1.9
2,171,581	+				-0.4
2,171,607	+				+1.8
2,171,607	+				+1.2
2,171,652	+				+0.9
2,171,676	+				+1.2
2,171,677	-				-0.5
2,171,677	-				-0.6
2,171,677	-				-0.2
2,171,758	-		Rv1920	0.16	-0.1
2,171,771	-		Rv1920	0.17	+0.6
2,172,061	+		Rv1920	0.51	-0.1
2,172,298	+		Rv1920	0.78	-0.2
2,172,298	+		Rv1920	0.78	-0.0
2,172,301	+		Rv1920	0.78	+0.1