Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1622c

Experiment: 7H9 with Meropenem 9.6 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1621c and Rv1622c are separated by 86 nucleotidesRv1622c and Rv1623c are separated by 29 nucleotides Rv1621c: Rv1621c - Probable 'component linked with the assembly of cytochrome' transport transmembrane ATP-binding protein ABC transporter CydD, at 1,821,690 to 1,823,273 Rv1621c Rv1622c: Rv1622c - Probable integral membrane cytochrome D ubiquinol oxidase (subunit II) CydB (cytochrome BD-I oxidase subunit II), at 1,823,360 to 1,824,400 Rv1622c Rv1623c: Rv1623c - Probable integral membrane cytochrome D ubiquinol oxidase (subunit I) CydA (cytochrome BD-I oxidase subunit I), at 1,824,430 to 1,825,887 Rv1623c Position (kb) 1823 1824 1825Strain fitness (log2 ratio) -2 -1 0 1at 1822.729 kb on - strand, within Rv1621cat 1822.940 kb on - strand, within Rv1621cat 1824.435 kb on - strandat 1824.435 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Meropenem 9.6 ug/mL
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1,822,729 - Rv1621c 0.66 -2.0
1,822,940 - Rv1621c 0.79 -2.1
1,824,435 - -0.8
1,824,435 - -0.2

Or see this region's nucleotide sequence