Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1468c

Experiment: 7H9 with Meropenem 9.6 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Meropenem 9.6 ug/mL
1,654,751	+		Rv1467c	0.59	-1.5
1,654,783	-		Rv1467c	0.61	-0.1
1,654,799	+		Rv1467c	0.62	+0.1
1,654,800	-		Rv1467c	0.62	-0.2
1,654,811	+		Rv1467c	0.62	-0.9
1,654,811	+		Rv1467c	0.62	-2.9
1,654,811	+		Rv1467c	0.62	-0.9
1,654,812	-		Rv1467c	0.62	-0.9
1,654,890	+		Rv1467c	0.67	-0.3
1,655,087	+		Rv1467c	0.77	-0.4
1,655,147	+		Rv1467c	0.81	+0.8
1,655,148	-		Rv1467c	0.81	-0.3
1,655,327	+				+1.6
1,655,492	+				+1.0
1,655,492	+				+0.8
1,655,493	-				+3.1
1,655,567	+				-0.8
1,655,568	-				-0.2
1,655,610	+				+0.7
1,655,611	-				+0.2
1,656,462	+		Rv1468c	0.77	+1.5
1,656,462	+		Rv1468c	0.77	+0.4
1,656,463	-		Rv1468c	0.77	+1.0
1,656,538	-		Rv1468c	0.83	+0.0
1,656,538	-		Rv1468c	0.83	-1.0
1,656,647	-				-0.4
1,656,746	-				-0.2
1,656,746	-				-0.3
1,656,758	-				-1.8
1,657,164	+		Rv1469	0.10	-0.9
1,657,164	+		Rv1469	0.10	-0.1
1,657,176	+		Rv1469	0.11	+0.1
1,657,177	-		Rv1469	0.11	+0.2
1,657,177	-		Rv1469	0.11	+0.6
1,657,633	+		Rv1469	0.34	+0.3
1,657,634	-		Rv1469	0.34	+0.3
1,657,634	-		Rv1469	0.34	-0.6