Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1366A

Experiment: 7H9 with Meropenem 9.6 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Meropenem 9.6 ug/mL
1,538,248	+				-0.5
1,538,248	+				-0.2
1,538,248	+				-0.6
1,538,248	+				-0.5
1,538,249	-				-0.3
1,538,249	-				+0.4
1,538,250	+				+0.4
1,538,250	+				-0.7
1,538,251	-				-1.4
1,538,251	-				+0.3
1,538,274	-				-0.5
1,538,276	-				+0.2
1,538,397	+				-0.8
1,538,407	-				+2.8
1,538,407	-				-1.5
1,538,604	+		Rv1366	0.26	-0.6
1,538,605	-		Rv1366	0.26	-0.6
1,538,605	-		Rv1366	0.26	+0.0
1,538,605	-		Rv1366	0.26	+0.9
1,538,605	-		Rv1366	0.26	-1.4
1,538,611	+		Rv1366	0.27	-0.2
1,538,611	+		Rv1366	0.27	-0.5
1,538,667	-		Rv1366	0.34	-0.2
1,538,667	-		Rv1366	0.34	+0.2
1,538,667	-		Rv1366	0.34	+2.2
1,538,913	-		Rv1366	0.64	-0.3
1,538,933	+		Rv1366	0.66	-0.2
1,538,933	+		Rv1366	0.66	-0.1
1,538,934	-		Rv1366	0.66	+0.0
1,538,934	-		Rv1366	0.66	+2.4
1,538,974	-		Rv1366	0.71	+0.3
1,539,160	+				-1.3
1,539,223	-		Rv1366A	0.16	-0.5
1,539,360	-		Rv1366A	0.69	-0.6
1,539,514	-				-0.4
1,539,531	+				-1.1
1,539,587	-				+0.0
1,539,642	+		Rv1367c	0.11	+1.0
1,539,643	-		Rv1367c	0.12	-0.3
1,539,643	-		Rv1367c	0.12	-0.2
1,539,651	-		Rv1367c	0.12	+0.8
1,539,651	-		Rv1367c	0.12	+0.6
1,539,651	-		Rv1367c	0.12	-1.0
1,539,770	+		Rv1367c	0.23	-0.5
1,539,771	-		Rv1367c	0.23	+0.6
1,540,050	+		Rv1367c	0.47	+0.3
1,540,050	+		Rv1367c	0.47	-0.7
1,540,089	+		Rv1367c	0.51	-1.7
1,540,089	+		Rv1367c	0.51	-1.5
1,540,090	-		Rv1367c	0.51	-0.2
1,540,090	-		Rv1367c	0.51	+0.3
1,540,090	-		Rv1367c	0.51	-0.7
1,540,207	-		Rv1367c	0.61	-0.1
1,540,207	-		Rv1367c	0.61	-0.2
1,540,300	-		Rv1367c	0.69	-1.0
1,540,300	-		Rv1367c	0.69	-0.4