Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1046c

Experiment: 7H9 with Meropenem 9.6 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Meropenem 9.6 ug/mL
1,167,716	+				-0.7
1,167,737	+				+0.5
1,167,944	+		Rv1045	0.31	-0.8
1,167,945	-		Rv1045	0.31	+0.2
1,168,035	+		Rv1045	0.41	-0.0
1,168,035	+		Rv1045	0.41	-1.7
1,168,035	+		Rv1045	0.41	-0.2
1,168,075	+		Rv1045	0.46	-0.4
1,168,250	+		Rv1045	0.65	-0.5
1,168,251	-		Rv1045	0.66	-0.7
1,168,373	+		Rv1045	0.79	-0.1
1,168,373	+		Rv1045	0.79	+0.1
1,168,442	-		Rv1045	0.87	-1.2
1,168,442	-		Rv1045	0.87	-0.3
1,168,442	-		Rv1045	0.87	-0.1
1,168,608	+				-0.3
1,168,683	+				-1.0
1,168,705	+				-0.2
1,168,706	-				-0.2
1,168,706	-				-0.6
1,168,836	+		Rv1046c	0.25	+1.4
1,168,837	-		Rv1046c	0.25	+0.3
1,168,837	-		Rv1046c	0.25	+0.1
1,168,926	+		Rv1046c	0.42	+0.5
1,169,288	+				+1.3
1,169,291	+				-0.0
1,169,291	+				-0.9
1,169,292	-				+0.4
1,169,292	-				-0.7
1,169,302	-				+0.3