Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0923c

Experiment: 7H9 with Meropenem 9.6 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0922 and Rv0923c are separated by 175 nucleotidesRv0923c and Rv0924c are separated by 0 nucleotides Rv0922: Rv0922 - Possible transposase, at 1,027,685 to 1,029,337 Rv0922 Rv0923c: Rv0923c - Conserved hypothetical protein, at 1,029,513 to 1,030,577 Rv0923c Rv0924c: Rv0924c - Divalent cation-transport integral membrane protein MntH (BRAMP) (MRAMP), at 1,030,578 to 1,031,864 Rv0924c Position (kb) 1029 1030 1031Strain fitness (log2 ratio) -2 -1 0 1at 1028.776 kb on - strand, within Rv0922at 1028.822 kb on + strand, within Rv0922at 1028.823 kb on - strand, within Rv0922at 1029.090 kb on + strand, within Rv0922at 1029.217 kb on + strandat 1029.217 kb on + strandat 1029.267 kb on + strandat 1029.268 kb on - strandat 1029.348 kb on - strandat 1029.348 kb on - strandat 1029.515 kb on - strandat 1029.515 kb on - strandat 1029.515 kb on - strandat 1029.515 kb on - strandat 1029.627 kb on + strand, within Rv0923cat 1029.922 kb on + strand, within Rv0923cat 1029.922 kb on + strand, within Rv0923cat 1029.922 kb on + strand, within Rv0923cat 1029.946 kb on + strand, within Rv0923cat 1029.946 kb on + strand, within Rv0923cat 1030.171 kb on + strand, within Rv0923cat 1030.171 kb on + strand, within Rv0923cat 1030.228 kb on - strand, within Rv0923cat 1030.231 kb on + strand, within Rv0923cat 1030.273 kb on + strand, within Rv0923cat 1030.273 kb on + strand, within Rv0923cat 1030.274 kb on - strand, within Rv0923cat 1030.274 kb on - strand, within Rv0923cat 1030.274 kb on - strand, within Rv0923cat 1030.555 kb on + strandat 1030.556 kb on - strandat 1030.556 kb on - strandat 1030.556 kb on - strandat 1030.737 kb on - strand, within Rv0924cat 1030.796 kb on + strand, within Rv0924cat 1030.827 kb on + strand, within Rv0924cat 1030.828 kb on - strand, within Rv0924cat 1030.891 kb on + strand, within Rv0924cat 1030.892 kb on - strand, within Rv0924c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Meropenem 9.6 ug/mL
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1,028,776 - Rv0922 0.66 -0.1
1,028,822 + Rv0922 0.69 -0.2
1,028,823 - Rv0922 0.69 -0.2
1,029,090 + Rv0922 0.85 -0.2
1,029,217 + +0.4
1,029,217 + -0.7
1,029,267 + +0.0
1,029,268 - -0.1
1,029,348 - -1.1
1,029,348 - -0.1
1,029,515 - -0.1
1,029,515 - +0.3
1,029,515 - +0.3
1,029,515 - -1.7
1,029,627 + Rv0923c 0.11 +0.3
1,029,922 + Rv0923c 0.38 +0.2
1,029,922 + Rv0923c 0.38 +0.4
1,029,922 + Rv0923c 0.38 +0.0
1,029,946 + Rv0923c 0.41 -0.1
1,029,946 + Rv0923c 0.41 -0.1
1,030,171 + Rv0923c 0.62 -0.3
1,030,171 + Rv0923c 0.62 +0.1
1,030,228 - Rv0923c 0.67 -0.1
1,030,231 + Rv0923c 0.67 -0.2
1,030,273 + Rv0923c 0.71 -0.1
1,030,273 + Rv0923c 0.71 -0.2
1,030,274 - Rv0923c 0.71 +0.3
1,030,274 - Rv0923c 0.71 +0.9
1,030,274 - Rv0923c 0.71 -0.2
1,030,555 + +0.3
1,030,556 - -1.3
1,030,556 - -0.4
1,030,556 - +0.6
1,030,737 - Rv0924c 0.12 +1.4
1,030,796 + Rv0924c 0.17 -0.2
1,030,827 + Rv0924c 0.19 -1.1
1,030,828 - Rv0924c 0.19 -2.2
1,030,891 + Rv0924c 0.24 -0.9
1,030,892 - Rv0924c 0.24 -0.4

Or see this region's nucleotide sequence