Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0901

Experiment: 7H9 with Meropenem 9.6 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0899 and Rv0900 are separated by 12 nucleotidesRv0900 and Rv0901 overlap by 1 nucleotidesRv0901 and Rv0902c are separated by 16 nucleotides Rv0899: Rv0899 - Outer membrane protein A OmpA, at 1,002,812 to 1,003,792 Rv0899 Rv0900: Rv0900 - Possible membrane protein, at 1,003,805 to 1,003,957 Rv0900 Rv0901: Rv0901 - Possible conserved exported or membrane protein, at 1,003,957 to 1,004,484 Rv0901 Rv0902c: Rv0902c - Two component sensor histidine kinase PrrB, at 1,004,501 to 1,005,841 Rv0902c Position (kb) 1003 1004 1005Strain fitness (log2 ratio) -1 0 1 2at 1003.521 kb on - strand, within Rv0899at 1003.616 kb on - strand, within Rv0899at 1003.662 kb on - strand, within Rv0899at 1003.790 kb on + strandat 1003.832 kb on + strand, within Rv0900at 1003.833 kb on - strand, within Rv0900at 1004.086 kb on - strand, within Rv0901at 1004.365 kb on + strand, within Rv0901at 1004.368 kb on + strand, within Rv0901at 1004.369 kb on - strand, within Rv0901at 1004.389 kb on + strand, within Rv0901at 1004.389 kb on + strand, within Rv0901at 1004.390 kb on - strand, within Rv0901at 1004.397 kb on + strand, within Rv0901

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Meropenem 9.6 ug/mL
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1,003,521 - Rv0899 0.72 -1.0
1,003,616 - Rv0899 0.82 +0.1
1,003,662 - Rv0899 0.87 +0.9
1,003,790 + -0.0
1,003,832 + Rv0900 0.18 -0.3
1,003,833 - Rv0900 0.18 -0.0
1,004,086 - Rv0901 0.24 +0.3
1,004,365 + Rv0901 0.77 +2.0
1,004,368 + Rv0901 0.78 +0.0
1,004,369 - Rv0901 0.78 +0.7
1,004,389 + Rv0901 0.82 +0.2
1,004,389 + Rv0901 0.82 +0.3
1,004,390 - Rv0901 0.82 -0.3
1,004,397 + Rv0901 0.83 +0.9

Or see this region's nucleotide sequence