Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0691c

Experiment: 7H9 with Meropenem 9.6 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0690c and Rv0691c overlap by 4 nucleotidesRv0691c and Rv0691A overlap by 9 nucleotidesRv0691A and Rv0692 overlap by 16 nucleotidesRv0692 and Rv0693 overlap by 4 nucleotides Rv0690c: Rv0690c - Conserved hypothetical protein, at 790,024 to 791,073 Rv0690c Rv0691c: Rv0691c - Probable transcriptional regulatory protein, at 791,070 to 791,666 Rv0691c Rv0691A: Rv0691A - Mycofactocin precursor protein, at 791,658 to 791,846 Rv0691A Rv0692: Rv0692 - Conserved hypothetical protein, at 791,831 to 792,160 Rv0692 Rv0693: Rv0693 - Probable coenzyme PQQ synthesis protein E PqqE (coenzyme PQQ synthesis protein III), at 792,157 to 793,332 Rv0693 Position (kb) 791 792Strain fitness (log2 ratio) -1 0 1at 790.101 kb on + strandat 790.102 kb on - strandat 790.105 kb on + strandat 790.106 kb on - strandat 790.106 kb on - strandat 790.106 kb on - strandat 790.106 kb on - strandat 790.113 kb on - strandat 790.244 kb on + strand, within Rv0690cat 790.245 kb on - strand, within Rv0690cat 790.413 kb on - strand, within Rv0690cat 790.577 kb on + strand, within Rv0690cat 790.628 kb on - strand, within Rv0690cat 790.998 kb on - strandat 790.998 kb on - strandat 791.167 kb on + strand, within Rv0691cat 791.284 kb on + strand, within Rv0691cat 791.284 kb on + strand, within Rv0691cat 791.284 kb on + strand, within Rv0691cat 791.285 kb on - strand, within Rv0691cat 791.285 kb on - strand, within Rv0691cat 791.299 kb on + strand, within Rv0691cat 791.841 kb on + strandat 791.917 kb on - strand, within Rv0692at 791.980 kb on + strand, within Rv0692at 791.980 kb on + strand, within Rv0692at 791.981 kb on - strand, within Rv0692at 792.099 kb on - strand, within Rv0692at 792.222 kb on + strandat 792.222 kb on + strandat 792.222 kb on + strandat 792.223 kb on - strandat 792.238 kb on + strandat 792.252 kb on - strandat 792.358 kb on + strand, within Rv0693at 792.419 kb on - strand, within Rv0693

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Meropenem 9.6 ug/mL
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790,101 + -0.4
790,102 - +0.0
790,105 + +0.0
790,106 - +0.2
790,106 - +0.4
790,106 - +0.3
790,106 - +0.5
790,113 - -0.2
790,244 + Rv0690c 0.21 -0.1
790,245 - Rv0690c 0.21 -0.7
790,413 - Rv0690c 0.37 +0.4
790,577 + Rv0690c 0.53 -1.5
790,628 - Rv0690c 0.58 +0.1
790,998 - -0.2
790,998 - +0.3
791,167 + Rv0691c 0.16 -1.0
791,284 + Rv0691c 0.36 -0.3
791,284 + Rv0691c 0.36 +0.4
791,284 + Rv0691c 0.36 -0.7
791,285 - Rv0691c 0.36 -1.2
791,285 - Rv0691c 0.36 -1.5
791,299 + Rv0691c 0.38 -0.5
791,841 + +0.6
791,917 - Rv0692 0.26 +0.1
791,980 + Rv0692 0.45 +0.2
791,980 + Rv0692 0.45 +0.8
791,981 - Rv0692 0.45 +0.0
792,099 - Rv0692 0.81 -0.3
792,222 + +0.0
792,222 + +1.5
792,222 + +0.6
792,223 - +0.2
792,238 + +1.2
792,252 - +0.1
792,358 + Rv0693 0.17 +0.2
792,419 - Rv0693 0.22 +0.1

Or see this region's nucleotide sequence