Experiment: 7H9 with Meropenem 9.6 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0640 and Rv0641 are separated by 66 nucleotides Rv0641 and Rv0642c are separated by 73 nucleotides Rv0642c and Rv0643c are separated by 64 nucleotides
Rv0640: Rv0640 - 50S ribosomal protein L11 RplK, at 735,022 to 735,450
Rv0640
Rv0641: Rv0641 - 50S ribosomal protein L1 RplA, at 735,517 to 736,224
Rv0641
Rv0642c: Rv0642c - Methoxy mycolic acid synthase 4 MmaA4 (methyl mycolic acid synthase 4) (MMA4) (hydroxy mycolic acid synthase), at 736,298 to 737,203
Rv0642c
Rv0643c: Rv0643c - Methoxy mycolic acid synthase 3 MmaA3 (methyl mycolic acid synthase 3) (MMA3) (hydroxy mycolic acid synthase), at 737,268 to 738,149
Rv0643c
Position (kb) 736
737
738 Strain fitness (log2 ratio) -2
-1
0
1
2
3 at 735.456 kb on + strand at 735.502 kb on + strand at 735.502 kb on + strand at 736.222 kb on + strand at 736.223 kb on - strand at 736.223 kb on - strand at 736.246 kb on + strand at 736.247 kb on - strand at 736.247 kb on - strand at 736.247 kb on - strand at 736.278 kb on + strand at 736.363 kb on - strand at 736.384 kb on - strand at 736.384 kb on - strand at 736.401 kb on + strand, within Rv0642c at 736.482 kb on + strand, within Rv0642c at 736.580 kb on + strand, within Rv0642c at 737.029 kb on - strand, within Rv0642c at 737.226 kb on - strand at 737.302 kb on + strand at 737.302 kb on + strand at 737.339 kb on - strand at 737.339 kb on - strand at 737.348 kb on - strand at 737.356 kb on + strand at 737.356 kb on + strand at 737.358 kb on + strand, within Rv0643c at 737.586 kb on + strand, within Rv0643c at 737.586 kb on + strand, within Rv0643c at 737.610 kb on + strand, within Rv0643c at 737.610 kb on + strand, within Rv0643c at 737.611 kb on - strand, within Rv0643c at 737.730 kb on + strand, within Rv0643c at 737.876 kb on - strand, within Rv0643c at 737.876 kb on - strand, within Rv0643c at 737.967 kb on + strand, within Rv0643c at 737.967 kb on + strand, within Rv0643c at 737.968 kb on - strand, within Rv0643c at 738.023 kb on - strand, within Rv0643c at 738.034 kb on + strand, within Rv0643c at 738.034 kb on + strand, within Rv0643c at 738.034 kb on + strand, within Rv0643c at 738.034 kb on + strand, within Rv0643c at 738.085 kb on + strand at 738.202 kb on + strand at 738.203 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Meropenem 9.6 ug/mL remove 735,456 + +0.1 735,502 + -0.4 735,502 + +0.1 736,222 + -0.4 736,223 - +0.8 736,223 - -0.2 736,246 + -0.2 736,247 - +0.1 736,247 - -0.2 736,247 - -0.3 736,278 + -1.5 736,363 - +3.2 736,384 - -1.3 736,384 - -0.8 736,401 + Rv0642c 0.11 -0.8 736,482 + Rv0642c 0.20 -0.6 736,580 + Rv0642c 0.31 +1.8 737,029 - Rv0642c 0.81 +1.4 737,226 - -1.0 737,302 + -0.1 737,302 + -0.9 737,339 - -0.3 737,339 - +2.2 737,348 - -0.6 737,356 + -0.3 737,356 + -0.7 737,358 + Rv0643c 0.10 -0.8 737,586 + Rv0643c 0.36 -0.0 737,586 + Rv0643c 0.36 -0.0 737,610 + Rv0643c 0.39 +0.5 737,610 + Rv0643c 0.39 -0.1 737,611 - Rv0643c 0.39 +0.5 737,730 + Rv0643c 0.52 -0.3 737,876 - Rv0643c 0.69 +0.8 737,876 - Rv0643c 0.69 +0.0 737,967 + Rv0643c 0.79 +0.7 737,967 + Rv0643c 0.79 +0.3 737,968 - Rv0643c 0.79 -2.5 738,023 - Rv0643c 0.86 -0.0 738,034 + Rv0643c 0.87 +0.7 738,034 + Rv0643c 0.87 +0.1 738,034 + Rv0643c 0.87 +0.6 738,034 + Rv0643c 0.87 -0.4 738,085 + +0.4 738,202 + +0.8 738,203 - -0.2
Or see this region's nucleotide sequence