Experiment: 7H9 with Meropenem 9.6 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0576 and Rv0577 are separated by 13 nucleotides Rv0577 and Rv0578c are separated by 44 nucleotides Rv0578c and Rv0579 are separated by 321 nucleotides
Rv0576: Rv0576 - Probable transcriptional regulatory protein (possibly ArsR-family), at 669,848 to 671,152
Rv0576
Rv0577: Rv0577 - Conserved protein TB27.3, at 671,166 to 671,951
Rv0577
Rv0578c: Rv0578c - PE-PGRS family protein PE_PGRS7, at 671,996 to 675,916
Rv0578c
Rv0579: Rv0579 - Conserved hypothetical protein, at 676,238 to 676,996
Rv0579
Position (kb) 671
672
673
674
675
676 Strain fitness (log2 ratio) -2
-1
0
1
2 at 670.998 kb on + strand, within Rv0576 at 671.151 kb on - strand at 671.251 kb on - strand, within Rv0577 at 671.311 kb on - strand, within Rv0577 at 671.311 kb on - strand, within Rv0577 at 671.403 kb on + strand, within Rv0577 at 671.403 kb on + strand, within Rv0577 at 671.403 kb on + strand, within Rv0577 at 671.403 kb on + strand, within Rv0577 at 671.404 kb on - strand, within Rv0577 at 671.404 kb on - strand, within Rv0577 at 671.542 kb on + strand, within Rv0577 at 671.542 kb on + strand, within Rv0577 at 671.687 kb on - strand, within Rv0577 at 671.687 kb on - strand, within Rv0577 at 671.787 kb on + strand, within Rv0577 at 671.949 kb on + strand at 671.949 kb on + strand at 671.950 kb on - strand at 671.997 kb on + strand at 672.179 kb on + strand at 672.923 kb on + strand, within Rv0578c at 674.177 kb on + strand, within Rv0578c at 674.178 kb on - strand, within Rv0578c at 675.217 kb on + strand, within Rv0578c at 675.354 kb on + strand, within Rv0578c at 675.354 kb on + strand, within Rv0578c at 675.355 kb on - strand, within Rv0578c at 675.355 kb on - strand, within Rv0578c at 675.440 kb on + strand, within Rv0578c at 675.510 kb on + strand, within Rv0578c at 675.510 kb on + strand, within Rv0578c at 675.660 kb on + strand at 675.988 kb on + strand at 675.988 kb on + strand at 675.988 kb on + strand at 675.989 kb on - strand at 675.989 kb on - strand at 676.043 kb on - strand at 676.043 kb on - strand at 676.085 kb on - strand at 676.144 kb on + strand at 676.145 kb on - strand at 676.145 kb on - strand at 676.159 kb on - strand at 676.232 kb on + strand at 676.233 kb on - strand at 676.247 kb on + strand at 676.379 kb on - strand, within Rv0579 at 676.460 kb on + strand, within Rv0579 at 676.465 kb on + strand, within Rv0579 at 676.466 kb on - strand, within Rv0579 at 676.523 kb on - strand, within Rv0579 at 676.523 kb on - strand, within Rv0579
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Meropenem 9.6 ug/mL remove 670,998 + Rv0576 0.88 -0.5 671,151 - -0.1 671,251 - Rv0577 0.11 -0.1 671,311 - Rv0577 0.18 +0.3 671,311 - Rv0577 0.18 +0.7 671,403 + Rv0577 0.30 -0.3 671,403 + Rv0577 0.30 -0.2 671,403 + Rv0577 0.30 -0.4 671,403 + Rv0577 0.30 -0.0 671,404 - Rv0577 0.30 +0.4 671,404 - Rv0577 0.30 -0.2 671,542 + Rv0577 0.48 -0.5 671,542 + Rv0577 0.48 +0.1 671,687 - Rv0577 0.66 +0.5 671,687 - Rv0577 0.66 -0.3 671,787 + Rv0577 0.79 -0.2 671,949 + +1.8 671,949 + +0.6 671,950 - +0.1 671,997 + -0.5 672,179 + -1.8 672,923 + Rv0578c 0.24 -0.4 674,177 + Rv0578c 0.56 +0.8 674,178 - Rv0578c 0.56 +1.8 675,217 + Rv0578c 0.82 +1.8 675,354 + Rv0578c 0.86 +0.3 675,354 + Rv0578c 0.86 -0.0 675,355 - Rv0578c 0.86 +0.7 675,355 - Rv0578c 0.86 -0.1 675,440 + Rv0578c 0.88 +0.2 675,510 + Rv0578c 0.90 +0.5 675,510 + Rv0578c 0.90 +0.2 675,660 + -0.7 675,988 + +0.3 675,988 + -0.4 675,988 + -0.7 675,989 - -0.4 675,989 - -0.2 676,043 - +0.2 676,043 - -0.1 676,085 - +1.8 676,144 + -0.6 676,145 - +1.8 676,145 - +0.1 676,159 - +1.3 676,232 + -1.0 676,233 - -0.2 676,247 + +0.3 676,379 - Rv0579 0.19 -0.2 676,460 + Rv0579 0.29 -0.5 676,465 + Rv0579 0.30 -0.2 676,466 - Rv0579 0.30 -1.0 676,523 - Rv0579 0.38 -0.1 676,523 - Rv0579 0.38 -0.3
Or see this region's nucleotide sequence