Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0564c

Experiment: 7H9 with Meropenem 9.6 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0563 and Rv0564c are separated by 184 nucleotidesRv0564c and Rv0565c are separated by 60 nucleotides Rv0563: Rv0563 - Probable protease transmembrane protein heat shock protein HtpX, at 653,879 to 654,739 Rv0563 Rv0564c: Rv0564c - Probable glycerol-3-phosphate dehydrogenase [NAD(P)+] GpdA1 (NAD(P)H-dependent glycerol-3-phosphate dehydrogenase) (NAD(P)H-dependent dihydroxyacetone-phosphate reductase), at 654,924 to 655,949 Rv0564c Rv0565c: Rv0565c - Probable monooxygenase, at 656,010 to 657,470 Rv0565c Position (kb) 654 655 656Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 654.021 kb on - strand, within Rv0563at 654.155 kb on + strand, within Rv0563at 654.468 kb on + strand, within Rv0563at 654.740 kb on + strandat 654.740 kb on + strandat 654.741 kb on - strandat 654.876 kb on - strandat 654.876 kb on - strandat 654.926 kb on - strandat 654.977 kb on + strandat 654.978 kb on - strandat 654.978 kb on - strandat 654.978 kb on - strandat 654.979 kb on + strandat 654.979 kb on + strandat 655.592 kb on + strand, within Rv0564cat 655.593 kb on - strand, within Rv0564cat 655.796 kb on + strand, within Rv0564cat 655.961 kb on + strandat 656.056 kb on + strandat 656.089 kb on - strandat 656.146 kb on + strandat 656.147 kb on - strandat 656.353 kb on + strand, within Rv0565cat 656.353 kb on + strand, within Rv0565cat 656.447 kb on + strand, within Rv0565cat 656.487 kb on - strand, within Rv0565cat 656.602 kb on + strand, within Rv0565cat 656.602 kb on + strand, within Rv0565cat 656.602 kb on + strand, within Rv0565cat 656.603 kb on - strand, within Rv0565cat 656.939 kb on - strand, within Rv0565c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Meropenem 9.6 ug/mL
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654,021 - Rv0563 0.16 -2.3
654,155 + Rv0563 0.32 -2.8
654,468 + Rv0563 0.68 -0.8
654,740 + -0.3
654,740 + +0.8
654,741 - -0.4
654,876 - -0.1
654,876 - -0.1
654,926 - -1.2
654,977 + -0.3
654,978 - -0.2
654,978 - +0.3
654,978 - +0.8
654,979 + -0.1
654,979 + -0.4
655,592 + Rv0564c 0.65 +0.0
655,593 - Rv0564c 0.65 +0.9
655,796 + Rv0564c 0.85 +0.5
655,961 + +0.3
656,056 + -0.7
656,089 - +0.6
656,146 + +0.5
656,147 - +1.0
656,353 + Rv0565c 0.23 -0.4
656,353 + Rv0565c 0.23 -0.9
656,447 + Rv0565c 0.30 -0.2
656,487 - Rv0565c 0.33 +0.8
656,602 + Rv0565c 0.41 -0.6
656,602 + Rv0565c 0.41 +0.4
656,602 + Rv0565c 0.41 +0.5
656,603 - Rv0565c 0.41 +0.3
656,939 - Rv0565c 0.64 +2.7

Or see this region's nucleotide sequence