Experiment: 7H9 with Meropenem 9.6 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0533c and Rv0534c are separated by 81 nucleotides Rv0534c and Rv0535 are separated by 16 nucleotides Rv0535 and Rv0536 overlap by 4 nucleotides
Rv0532: Rv0532 - PE-PGRS family protein PE_PGRS6, at 622,793 to 624,577
Rv0532
Rv0533c: Rv0533c - 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III), at 624,473 to 625,480
Rv0533c
Rv0534c: Rv0534c - 1,4-dihydroxy-2-naphthoate octaprenyltransferase MenA (DHNA-octaprenyltransferase), at 625,562 to 626,440
Rv0534c
Rv0535: Rv0535 - Probable 5'-methylthioadenosine phosphorylase Pnp (MTA phosphorylase), at 626,457 to 627,251
Rv0535
Rv0536: Rv0536 - Probable UDP-glucose 4-epimerase GalE3 (galactowaldenase) (UDP-galactose 4-epimerase) (uridine diphosphate galactose 4-epimerase) (uridine diphospho-galactose 4-epimerase), at 627,248 to 628,288
Rv0536
Position (kb) 625
626
627 Strain fitness (log2 ratio) -2
-1
0
1
2 at 624.575 kb on + strand at 624.632 kb on - strand, within Rv0533c at 624.697 kb on + strand, within Rv0533c at 624.726 kb on - strand, within Rv0533c at 624.726 kb on - strand, within Rv0533c at 624.885 kb on - strand, within Rv0533c at 625.005 kb on + strand, within Rv0533c at 625.006 kb on - strand, within Rv0533c at 625.006 kb on - strand, within Rv0533c at 625.006 kb on - strand, within Rv0533c at 625.006 kb on - strand, within Rv0533c at 625.013 kb on + strand, within Rv0533c at 625.013 kb on + strand, within Rv0533c at 625.014 kb on - strand, within Rv0533c at 625.014 kb on - strand, within Rv0533c at 625.102 kb on - strand, within Rv0533c at 625.142 kb on + strand, within Rv0533c at 625.350 kb on + strand, within Rv0533c at 625.385 kb on + strand at 625.385 kb on + strand at 625.386 kb on - strand at 625.419 kb on + strand at 625.481 kb on - strand at 625.489 kb on + strand at 625.489 kb on + strand at 625.490 kb on - strand at 625.490 kb on - strand at 625.490 kb on - strand at 625.563 kb on + strand at 625.564 kb on - strand at 626.456 kb on + strand at 626.457 kb on - strand at 626.505 kb on + strand at 626.506 kb on - strand at 626.506 kb on - strand at 626.811 kb on + strand, within Rv0535 at 626.812 kb on - strand, within Rv0535 at 626.812 kb on - strand, within Rv0535 at 626.812 kb on - strand, within Rv0535
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Meropenem 9.6 ug/mL remove 624,575 + +0.1 624,632 - Rv0533c 0.16 -0.9 624,697 + Rv0533c 0.22 -0.6 624,726 - Rv0533c 0.25 -0.6 624,726 - Rv0533c 0.25 -0.2 624,885 - Rv0533c 0.41 +0.0 625,005 + Rv0533c 0.53 +0.2 625,006 - Rv0533c 0.53 -0.1 625,006 - Rv0533c 0.53 +0.6 625,006 - Rv0533c 0.53 -0.0 625,006 - Rv0533c 0.53 +0.0 625,013 + Rv0533c 0.54 -2.6 625,013 + Rv0533c 0.54 -0.3 625,014 - Rv0533c 0.54 -0.8 625,014 - Rv0533c 0.54 -0.2 625,102 - Rv0533c 0.62 -0.0 625,142 + Rv0533c 0.66 +0.2 625,350 + Rv0533c 0.87 -0.2 625,385 + +2.6 625,385 + +0.6 625,386 - -0.5 625,419 + -0.5 625,481 - -0.1 625,489 + -0.8 625,489 + -0.3 625,490 - +0.5 625,490 - +1.8 625,490 - -0.1 625,563 + -0.5 625,564 - +0.0 626,456 + +1.1 626,457 - -0.2 626,505 + -0.0 626,506 - -0.2 626,506 - -0.1 626,811 + Rv0535 0.45 -0.2 626,812 - Rv0535 0.45 +0.0 626,812 - Rv0535 0.45 -0.1 626,812 - Rv0535 0.45 -0.8
Or see this region's nucleotide sequence