Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3814c

Experiment: 7H9 with Meropenem 9.6 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Meropenem 9.6 ug/mL
4,278,395	+				+1.9
4,278,663	-		Rv3813c	0.33	+0.7
4,278,735	+		Rv3813c	0.41	-0.5
4,278,821	+		Rv3813c	0.52	-0.6
4,278,822	-		Rv3813c	0.52	+0.4
4,279,108	+		Rv3813c	0.87	-1.1
4,279,109	-		Rv3813c	0.87	+0.2
4,279,396	+		Rv3814c	0.21	-1.4
4,279,407	+		Rv3814c	0.23	-1.6
4,279,407	+		Rv3814c	0.23	-1.1
4,279,584	-		Rv3814c	0.45	-1.2
4,279,658	+		Rv3814c	0.54	+1.9
4,279,675	-		Rv3814c	0.57	-1.4
4,279,778	-		Rv3814c	0.70	-2.1
4,279,791	+		Rv3814c	0.71	-1.6
4,279,792	-		Rv3814c	0.72	-1.4
4,279,876	+		Rv3814c	0.82	-1.3
4,279,877	-		Rv3814c	0.82	-0.9
4,279,877	-		Rv3814c	0.82	-0.8
4,279,877	-		Rv3814c	0.82	-2.8
4,280,017	+				-2.1
4,280,018	-				-0.6
4,280,018	-				-2.9
4,280,018	-				+0.5
4,280,034	+				-1.7
4,280,270	+		Rv3815c	0.31	-0.5
4,280,297	+		Rv3815c	0.35	-1.8
4,280,297	+		Rv3815c	0.35	-1.2
4,280,298	-		Rv3815c	0.35	-0.1
4,280,493	+		Rv3815c	0.61	+1.9
4,280,649	+		Rv3815c	0.81	-2.0
4,280,649	+		Rv3815c	0.81	-0.6
4,280,650	-		Rv3815c	0.82	+0.6
4,280,650	-		Rv3815c	0.82	-0.2
4,280,650	-		Rv3815c	0.82	-0.6
4,280,650	-		Rv3815c	0.82	-1.6
4,280,650	-		Rv3815c	0.82	+0.2
4,280,650	-		Rv3815c	0.82	-0.1
4,280,666	-		Rv3815c	0.84	-0.1
4,280,712	+		Rv3815c	0.90	-1.7
4,280,713	-				-0.6
4,280,845	+				-1.8
4,280,846	-				+0.2
4,280,846	-				-0.2
4,280,950	-		Rv3816c	0.20	-0.2