Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3049c

Experiment: 7H9 with Meropenem 9.6 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Meropenem 9.6 ug/mL
3,409,359	-				-0.1
3,409,431	-				-0.1
3,409,431	-				-0.6
3,409,451	+				-0.4
3,409,452	-				+0.3
3,409,510	+				-1.5
3,409,511	-				+0.8
3,409,663	+				+1.8
3,409,808	-		Rv3049c	0.19	-0.1
3,409,808	-		Rv3049c	0.19	+0.6
3,409,984	+		Rv3049c	0.30	-0.4
3,409,984	+		Rv3049c	0.30	+0.0
3,409,984	+		Rv3049c	0.30	-0.3
3,409,984	+		Rv3049c	0.30	-0.1
3,409,984	+		Rv3049c	0.30	-0.6
3,409,984	+		Rv3049c	0.30	-0.1
3,409,984	+		Rv3049c	0.30	-0.5
3,409,985	-		Rv3049c	0.30	+0.5
3,409,985	-		Rv3049c	0.30	+0.1
3,409,988	+		Rv3049c	0.30	+1.8
3,409,988	+		Rv3049c	0.30	+0.5
3,409,988	+		Rv3049c	0.30	-0.0
3,409,988	+		Rv3049c	0.30	+0.3
3,409,988	+		Rv3049c	0.30	-0.5
3,409,989	-		Rv3049c	0.30	+0.2
3,409,989	-		Rv3049c	0.30	+0.4
3,409,989	-		Rv3049c	0.30	-0.1
3,409,989	-		Rv3049c	0.30	+0.7
3,409,990	+		Rv3049c	0.31	+1.0
3,409,990	+		Rv3049c	0.31	-0.4
3,409,990	+		Rv3049c	0.31	-0.1
3,409,990	+		Rv3049c	0.31	+0.2
3,409,991	-		Rv3049c	0.31	-0.5
3,409,991	-		Rv3049c	0.31	-0.8
3,410,020	+		Rv3049c	0.32	-0.3
3,410,147	-		Rv3049c	0.41	-0.8
3,410,147	-		Rv3049c	0.41	-0.7
3,410,147	-		Rv3049c	0.41	+0.0
3,410,149	+		Rv3049c	0.41	-0.0
3,410,149	+		Rv3049c	0.41	+1.2
3,410,149	+		Rv3049c	0.41	+0.6
3,410,149	+		Rv3049c	0.41	+0.4
3,410,149	+		Rv3049c	0.41	-2.4
3,410,150	-		Rv3049c	0.41	-0.5
3,410,150	-		Rv3049c	0.41	+0.2
3,410,150	-		Rv3049c	0.41	-0.5
3,410,150	-		Rv3049c	0.41	-0.8
3,410,154	-		Rv3049c	0.41	+0.3
3,410,240	+		Rv3049c	0.46	-0.5
3,410,241	-		Rv3049c	0.46	-0.1
3,410,241	-		Rv3049c	0.46	-0.2
3,410,241	-		Rv3049c	0.46	+0.1
3,410,246	-		Rv3049c	0.47	-0.4
3,410,254	+		Rv3049c	0.47	+0.3
3,410,437	+		Rv3049c	0.59	-1.0
3,410,438	-		Rv3049c	0.59	-0.3
3,410,537	+		Rv3049c	0.65	-0.3
3,410,656	+		Rv3049c	0.73	-0.4
3,410,656	+		Rv3049c	0.73	+0.2
3,410,710	+		Rv3049c	0.76	+0.2
3,410,743	+		Rv3049c	0.78	+0.3
3,410,758	+		Rv3049c	0.79	-1.2
3,410,758	+		Rv3049c	0.79	+1.1
3,410,759	-		Rv3049c	0.79	-0.1
3,410,759	-		Rv3049c	0.79	-0.3
3,410,851	+		Rv3049c	0.85	-0.1
3,410,852	-		Rv3049c	0.85	+0.4
3,410,852	-		Rv3049c	0.85	-0.4
3,410,852	-		Rv3049c	0.85	-0.2
3,410,852	-		Rv3049c	0.85	-0.2
3,410,934	+				+0.9
3,410,934	+				+0.8
3,411,017	+				+0.2
3,411,017	+				+0.5
3,411,017	+				-0.8
3,411,018	-				-0.3
3,411,021	+				+0.3
3,411,617	+		Rv3050c	0.54	-0.8
3,411,617	+		Rv3050c	0.54	-1.4
3,411,618	-		Rv3050c	0.54	-0.9