Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2998

Experiment: 7H9 with Meropenem 9.6 ug/mL

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv2997 and Rv2998 are separated by 273 nucleotidesRv2998 and Rv2998A overlap by 52 nucleotidesRv2998A and Rv2999 are separated by 173 nucleotides Rv2997: Rv2997 - Possible alanine rich dehydrogenase, at 3,355,099 to 3,356,541 Rv2997 Rv2998: Rv2998 - Hypothetical protein, at 3,356,815 to 3,357,276 Rv2998 Rv2998A: Rv2998A - Conserved hypothetical protein, at 3,357,225 to 3,357,428 Rv2998A Rv2999: Rv2999 - Probable conserved lipoprotein LppY, at 3,357,602 to 3,358,567 Rv2999 Position (kb) 3356 3357 3358Strain fitness (log2 ratio) -1 0 1 2at 3356.162 kb on - strand, within Rv2997at 3356.306 kb on - strand, within Rv2997at 3356.407 kb on + strandat 3356.937 kb on + strand, within Rv2998at 3356.938 kb on - strand, within Rv2998at 3356.938 kb on - strand, within Rv2998at 3356.938 kb on - strand, within Rv2998at 3357.234 kb on + strandat 3357.458 kb on - strandat 3357.458 kb on - strandat 3357.660 kb on + strandat 3357.661 kb on - strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Meropenem 9.6 ug/mL
remove
3,356,162 - Rv2997 0.74 -0.4
3,356,306 - Rv2997 0.84 -0.4
3,356,407 + +0.2
3,356,937 + Rv2998 0.26 +0.4
3,356,938 - Rv2998 0.27 -0.2
3,356,938 - Rv2998 0.27 +0.3
3,356,938 - Rv2998 0.27 +0.1
3,357,234 + +2.7
3,357,458 - -0.8
3,357,458 - -0.1
3,357,660 + -0.3
3,357,661 - -0.3

Or see this region's nucleotide sequence