Experiment: 7H9 with Meropenem 9.6 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv2992c and Rv2993c overlap by 4 nucleotides Rv2993c and Rv2994 are separated by 275 nucleotides Rv2994 and Rv2995c overlap by 149 nucleotides Rv2995c and Rv2996c are separated by 14 nucleotides
Rv2992c: Rv2992c - Glutamyl-tRNA synthetase GltS (glutamate--tRNA ligase) (glutamyl-tRNA synthase) (GLURS), at 3,348,805 to 3,350,277
Rv2992c
Rv2993c: Rv2993c - Possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase), at 3,350,274 to 3,350,993
Rv2993c
Rv2994: Rv2994 - Probable conserved integral membrane protein, at 3,351,269 to 3,352,606
Rv2994
Rv2995c: Rv2995c - Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH), at 3,352,458 to 3,353,468
Rv2995c
Rv2996c: Rv2996c - Probable D-3-phosphoglycerate dehydrogenase SerA1 (PGDH), at 3,353,483 to 3,355,069
Rv2996c
Position (kb)
3351
3352
3353 Strain fitness (log2 ratio)
-1
0
1
2 at 3350.416 kb on - strand, within Rv2993c at 3350.664 kb on - strand, within Rv2993c at 3350.664 kb on - strand, within Rv2993c at 3351.409 kb on - strand, within Rv2994 at 3351.545 kb on + strand, within Rv2994 at 3351.916 kb on - strand, within Rv2994 at 3352.032 kb on + strand, within Rv2994 at 3352.181 kb on + strand, within Rv2994 at 3352.182 kb on - strand, within Rv2994 at 3352.271 kb on + strand, within Rv2994 at 3352.306 kb on + strand, within Rv2994 at 3352.307 kb on - strand, within Rv2994
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Meropenem 9.6 ug/mL remove 3,350,416 - Rv2993c 0.20 +0.4 3,350,664 - Rv2993c 0.54 +0.2 3,350,664 - Rv2993c 0.54 +0.8 3,351,409 - Rv2994 0.10 +1.4 3,351,545 + Rv2994 0.21 +0.2 3,351,916 - Rv2994 0.48 -1.4 3,352,032 + Rv2994 0.57 +0.3 3,352,181 + Rv2994 0.68 +2.0 3,352,182 - Rv2994 0.68 -0.3 3,352,271 + Rv2994 0.75 -0.0 3,352,306 + Rv2994 0.78 -0.7 3,352,307 - Rv2994 0.78 -0.1
Or see this region's nucleotide sequence