Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2710

Experiment: 7H9 with Meropenem 9.6 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Meropenem 9.6 ug/mL
3,021,497	+				+0.1
3,021,497	+				-0.4
3,021,498	-				+0.4
3,021,498	-				+0.1
3,021,498	-				+0.1
3,021,570	+				-0.8
3,021,570	+				+0.1
3,021,570	+				-0.1
3,021,702	+		Rv2708c	0.62	-0.8
3,021,712	-		Rv2708c	0.66	+0.1
3,021,763	+		Rv2708c	0.86	+0.7
3,021,764	-		Rv2708c	0.87	+0.8
3,021,787	+				+0.5
3,021,788	-				-1.2
3,021,788	-				-0.3
3,021,788	-				+0.2
3,021,850	+				+0.1
3,021,850	+				+0.0
3,021,850	+				-0.1
3,021,850	+				-0.2
3,021,850	+				-0.3
3,021,850	+				-0.2
3,021,851	-				-0.9
3,021,959	+		Rv2709	0.27	-0.6
3,021,959	+		Rv2709	0.27	-0.0
3,021,960	-		Rv2709	0.27	+0.0
3,021,988	+		Rv2709	0.33	+0.4
3,021,988	+		Rv2709	0.33	-1.1
3,021,988	+		Rv2709	0.33	-1.2
3,021,988	+		Rv2709	0.33	-0.3
3,021,989	-		Rv2709	0.34	+0.2
3,021,989	-		Rv2709	0.34	-0.6
3,021,989	-		Rv2709	0.34	+0.3
3,021,992	+		Rv2709	0.34	-0.3
3,022,773	+		Rv2710	0.32	+0.2
3,023,421	+				+1.0
3,023,454	+				-0.1
3,023,464	+				+0.4
3,023,490	+				-0.1
3,024,271	+				-1.4
3,024,272	-				+0.1