Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2684

Experiment: 7H9 with Meropenem 9.6 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Meropenem 9.6 ug/mL
2,999,979	+				+0.3
2,999,980	-				+0.7
2,999,980	-				-0.0
2,999,980	-				+0.1
2,999,980	-				+0.4
3,000,043	+				-1.5
3,000,112	-				+0.2
3,000,112	-				+0.0
3,000,119	+				+0.3
3,000,119	+				+0.9
3,000,119	+				+1.8
3,000,120	-				+1.6
3,000,120	-				+0.5
3,000,344	-		Rv2683	0.47	-0.4
3,000,344	-		Rv2683	0.47	+0.4
3,000,729	-				+0.5
3,000,752	+		Rv2684	0.11	+0.1
3,000,849	-		Rv2684	0.18	+0.6
3,000,947	-		Rv2684	0.26	+0.5
3,000,947	-		Rv2684	0.26	-0.5
3,001,156	-		Rv2684	0.42	+1.1
3,001,421	+		Rv2684	0.63	+0.3
3,001,425	+		Rv2684	0.63	+3.2
3,001,425	+		Rv2684	0.63	-0.0
3,001,426	-		Rv2684	0.63	+0.3
3,001,426	-		Rv2684	0.63	+0.1
3,001,569	+		Rv2684	0.74	-0.3
3,001,569	+		Rv2684	0.74	+0.3
3,001,569	+		Rv2684	0.74	-0.5
3,001,912	-				+0.9
3,001,912	-				-0.3
3,001,912	-				+1.0
3,001,928	+				-1.0
3,001,929	-				-0.1
3,001,929	-				-0.3
3,002,121	+		Rv2685	0.11	+0.1
3,002,122	-		Rv2685	0.11	+0.9
3,002,218	-		Rv2685	0.18	+1.0
3,002,218	-		Rv2685	0.18	-0.1
3,002,218	-		Rv2685	0.18	-0.4
3,002,218	-		Rv2685	0.18	-0.2
3,002,359	+		Rv2685	0.29	+0.5
3,002,360	-		Rv2685	0.29	+0.8