Experiment: 7H9 with Meropenem 9.6 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv2610c and Rv2611c are separated by 10 nucleotides Rv2611c and Rv2612c overlap by 4 nucleotides Rv2612c and Rv2613c overlap by 4 nucleotides Rv2613c and Rv2614c overlap by 8 nucleotides
Rv2610c: Rv2610c - Alpha-mannosyltransferase PimA, at 2,937,865 to 2,939,001
Rv2610c
Rv2611c: Rv2611c - Probable acyltransferase, at 2,939,012 to 2,939,962
Rv2611c
Rv2612c: Rv2612c - PI synthase PgsA1 (phosphatidylinositol synthase) (CDP-diacylglycerol--inositol-3-phosphatidyltransferase), at 2,939,959 to 2,940,612
Rv2612c
Rv2613c: Rv2613c - Conserved protein, at 2,940,609 to 2,941,196
Rv2613c
Rv2614c: Rv2614c - Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase), at 2,941,189 to 2,943,267
Rv2614c
Position (kb)
2939
2940
2941 Strain fitness (log2 ratio)
-3
-2
-1
0
1 at 2939.948 kb on - strand at 2940.778 kb on - strand, within Rv2613c at 2940.778 kb on - strand, within Rv2613c at 2940.938 kb on - strand, within Rv2613c at 2941.085 kb on - strand, within Rv2613c at 2941.085 kb on - strand, within Rv2613c at 2941.225 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Meropenem 9.6 ug/mL remove 2,939,948 - -3.3 2,940,778 - Rv2613c 0.29 +0.9 2,940,778 - Rv2613c 0.29 +0.8 2,940,938 - Rv2613c 0.56 -0.6 2,941,085 - Rv2613c 0.81 -0.4 2,941,085 - Rv2613c 0.81 -0.6 2,941,225 - -1.6
Or see this region's nucleotide sequence