Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2119

Experiment: 7H9 with Meropenem 9.6 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Meropenem 9.6 ug/mL
2,377,439	+				+1.1
2,377,440	-				-0.9
2,377,440	-				-1.9
2,377,494	-				+2.2
2,377,494	-				-0.3
2,377,559	+		Rv2118c	0.11	+0.4
2,377,600	-		Rv2118c	0.15	-0.0
2,377,708	+		Rv2118c	0.28	+0.5
2,377,709	-		Rv2118c	0.28	+0.0
2,377,924	+		Rv2118c	0.54	-0.1
2,378,022	+		Rv2118c	0.65	+0.2
2,378,022	+		Rv2118c	0.65	-1.1
2,378,023	-		Rv2118c	0.66	-0.1
2,378,062	+		Rv2118c	0.70	-0.7
2,378,062	+		Rv2118c	0.70	-0.5
2,378,099	-		Rv2118c	0.75	-1.3
2,378,375	-				-0.3
2,378,468	+				+0.1
2,378,469	-				-0.1
2,378,469	-				-0.3
2,378,469	-				+0.7
2,378,522	+		Rv2119	0.16	+0.2
2,378,560	+		Rv2119	0.21	-0.3
2,378,561	-		Rv2119	0.21	-0.2
2,378,561	-		Rv2119	0.21	+1.4
2,378,561	-		Rv2119	0.21	+0.6
2,378,561	-		Rv2119	0.21	+1.4
2,378,720	-		Rv2119	0.40	+1.9
2,378,722	+		Rv2119	0.40	-0.1
2,378,863	+		Rv2119	0.57	-0.8
2,378,863	+		Rv2119	0.57	+1.2
2,378,863	+		Rv2119	0.57	-0.6
2,378,864	-		Rv2119	0.57	+1.3
2,378,910	+		Rv2119	0.63	-0.1
2,378,911	-		Rv2119	0.63	+0.7
2,378,992	+		Rv2119	0.72	-0.3
2,378,993	-		Rv2119	0.73	+1.0
2,379,041	+		Rv2119	0.78	-0.3
2,379,082	-		Rv2119	0.83	+0.1
2,379,248	+				+0.2
2,379,248	+				+0.2
2,379,248	+				-0.8
2,379,355	+		Rv2120c	0.23	-0.2
2,379,356	-		Rv2120c	0.23	-1.1
2,379,502	+		Rv2120c	0.53	+0.3