Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2114

Experiment: 7H9 with Meropenem 9.6 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Meropenem 9.6 ug/mL
2,372,943	+		Rv2113	0.26	-0.6
2,373,177	+		Rv2113	0.46	+0.2
2,373,178	-		Rv2113	0.46	-1.2
2,373,178	-		Rv2113	0.46	+0.3
2,373,206	+		Rv2113	0.48	-0.7
2,373,206	+		Rv2113	0.48	-0.7
2,373,206	+		Rv2113	0.48	-0.2
2,373,206	+		Rv2113	0.48	-0.0
2,373,206	+		Rv2113	0.48	-1.0
2,373,207	-		Rv2113	0.48	-0.5
2,373,207	-		Rv2113	0.48	+0.9
2,373,207	-		Rv2113	0.48	-1.3
2,373,207	-		Rv2113	0.48	-0.6
2,373,207	-		Rv2113	0.48	-0.5
2,373,207	-		Rv2113	0.48	+0.6
2,373,207	-		Rv2113	0.48	-0.4
2,373,207	-		Rv2113	0.48	-0.4
2,373,484	-		Rv2113	0.72	-0.2
2,373,507	+		Rv2113	0.73	-0.4
2,373,507	+		Rv2113	0.73	-0.1
2,373,509	+		Rv2113	0.74	-0.3
2,373,510	-		Rv2113	0.74	-0.2
2,373,510	-		Rv2113	0.74	-0.6
2,373,567	-		Rv2113	0.78	-0.3
2,373,628	+		Rv2113	0.84	-1.2
2,373,628	+		Rv2113	0.84	+0.8
2,373,628	+		Rv2113	0.84	-0.4
2,373,629	-		Rv2113	0.84	+0.0
2,373,629	-		Rv2113	0.84	-0.4
2,373,629	-		Rv2113	0.84	+0.1
2,373,629	-		Rv2113	0.84	-0.3
2,373,629	-		Rv2113	0.84	+3.6
2,373,629	-		Rv2113	0.84	-0.0
2,373,629	-		Rv2113	0.84	+0.8
2,373,662	+		Rv2113	0.86	-1.7
2,373,662	+		Rv2113	0.86	+0.1
2,373,663	-		Rv2113	0.87	-1.8
2,373,663	-		Rv2113	0.87	-0.5
2,373,663	-		Rv2113	0.87	+0.1
2,373,663	-		Rv2113	0.87	-0.5
2,373,663	-		Rv2113	0.87	-0.2
2,373,663	-		Rv2113	0.87	-0.2
2,373,663	-		Rv2113	0.87	-0.6
2,373,663	-		Rv2113	0.87	+0.4
2,373,822	-				-0.1
2,373,931	-		Rv2114	0.16	-0.1
2,374,161	+		Rv2114	0.52	-1.3
2,374,162	-		Rv2114	0.53	-0.4
2,374,221	+		Rv2114	0.62	-0.5
2,374,221	+		Rv2114	0.62	-0.0
2,374,350	+		Rv2114	0.83	-1.9
2,374,350	+		Rv2114	0.83	+0.2
2,374,350	+		Rv2114	0.83	-0.1
2,374,351	-		Rv2114	0.83	-1.5
2,374,351	-		Rv2114	0.83	-0.2
2,374,351	-		Rv2114	0.83	-0.4
2,374,351	-		Rv2114	0.83	-0.7
2,374,355	+		Rv2114	0.83	+0.2
2,374,391	+		Rv2114	0.89	-2.0
2,374,391	+		Rv2114	0.89	-0.6
2,374,391	+		Rv2114	0.89	-0.7
2,374,392	-		Rv2114	0.89	-0.2
2,374,437	+				-0.9
2,374,437	+				+0.5
2,374,437	+				-0.5
2,374,438	-				-0.8
2,374,438	-				-0.3
2,374,463	-				+0.2