Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2023A

Experiment: 7H9 with Meropenem 9.6 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Meropenem 9.6 ug/mL
2,267,418	+		Rv2022c	0.49	+0.3
2,267,438	+		Rv2022c	0.53	+0.1
2,267,439	-		Rv2022c	0.53	+0.2
2,267,515	+		Rv2022c	0.65	-0.1
2,267,515	+		Rv2022c	0.65	+2.4
2,267,516	-		Rv2022c	0.66	-0.1
2,267,546	+		Rv2022c	0.70	-0.1
2,267,558	+		Rv2022c	0.72	-0.1
2,267,580	+		Rv2022c	0.76	+0.0
2,267,641	+		Rv2022c	0.86	-1.3
2,267,641	+		Rv2022c	0.86	+0.7
2,267,641	+		Rv2022c	0.86	-1.1
2,267,642	-		Rv2022c	0.86	+0.8
2,267,674	+				-2.7
2,267,674	+				+0.8
2,267,675	-				+0.5
2,267,684	+				+1.1
2,267,684	+				-0.0
2,267,684	+				-0.6
2,267,871	+		Rv2023c	0.34	+0.0
2,268,032	+		Rv2023c	0.79	-0.2
2,268,032	+		Rv2023c	0.79	-0.1
2,268,032	+		Rv2023c	0.79	-0.0
2,268,154	+				+0.6
2,268,158	+				-0.3
2,268,253	+				+0.1
2,268,254	-				-0.5
2,268,264	+				-0.1
2,268,364	-		Rv2023A	0.21	-0.5
2,268,487	+		Rv2023A	0.48	-0.8
2,268,549	-		Rv2023A	0.61	+0.1
2,268,556	+		Rv2023A	0.63	-0.4
2,268,594	+		Rv2023A	0.71	-0.5
2,268,630	-		Rv2023A	0.79	-0.0
2,268,695	-				-0.9
2,268,695	-				+0.7
2,269,012	+		Rv2024c	0.21	-0.0
2,269,013	-		Rv2024c	0.21	+0.4
2,269,169	+		Rv2024c	0.31	+0.4
2,269,169	+		Rv2024c	0.31	+0.1
2,269,169	+		Rv2024c	0.31	-0.2
2,269,170	-		Rv2024c	0.31	-0.3
2,269,170	-		Rv2024c	0.31	+0.3
2,269,171	+		Rv2024c	0.31	-0.1
2,269,172	-		Rv2024c	0.31	+0.4
2,269,195	+		Rv2024c	0.32	+0.5
2,269,195	+		Rv2024c	0.32	+0.9
2,269,196	-		Rv2024c	0.32	-1.8
2,269,196	-		Rv2024c	0.32	-0.2
2,269,343	-		Rv2024c	0.42	-1.5
2,269,343	-		Rv2024c	0.42	+0.7
2,269,405	-		Rv2024c	0.46	+0.4
2,269,451	-		Rv2024c	0.49	+1.8