Experiment: 7H9 with Meropenem 9.6 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv1964 and Rv1965 are separated by 9 nucleotides Rv1965 and Rv1966 are separated by 4 nucleotides Rv1966 and Rv1967 overlap by 4 nucleotides
Rv1964: Rv1964 - Conserved hypothetical integral membrane protein YrbE3A, at 2,207,700 to 2,208,497
Rv1964
Rv1965: Rv1965 - Conserved hypothetical integral membrane protein YrbE3B, at 2,208,507 to 2,209,322
Rv1965
Rv1966: Rv1966 - Mce-family protein Mce3A, at 2,209,327 to 2,210,604
Rv1966
Rv1967: Rv1967 - Mce-family protein Mce3B, at 2,210,601 to 2,211,629
Rv1967
Position (kb)
2209
2210
2211 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 2208.361 kb on - strand, within Rv1964 at 2208.363 kb on - strand, within Rv1964 at 2208.363 kb on - strand, within Rv1964 at 2208.363 kb on - strand, within Rv1964 at 2208.363 kb on - strand, within Rv1964 at 2208.741 kb on + strand, within Rv1965 at 2208.864 kb on - strand, within Rv1965 at 2208.942 kb on + strand, within Rv1965 at 2209.017 kb on + strand, within Rv1965 at 2209.018 kb on - strand, within Rv1965 at 2209.018 kb on - strand, within Rv1965 at 2209.050 kb on + strand, within Rv1965 at 2209.050 kb on + strand, within Rv1965 at 2209.051 kb on - strand, within Rv1965 at 2209.051 kb on - strand, within Rv1965 at 2209.051 kb on - strand, within Rv1965 at 2209.051 kb on - strand, within Rv1965 at 2209.071 kb on + strand, within Rv1965 at 2209.071 kb on + strand, within Rv1965 at 2209.072 kb on - strand, within Rv1965 at 2209.081 kb on - strand, within Rv1965 at 2209.081 kb on - strand, within Rv1965 at 2209.170 kb on + strand, within Rv1965 at 2209.170 kb on + strand, within Rv1965 at 2209.171 kb on - strand, within Rv1965 at 2209.171 kb on - strand, within Rv1965 at 2209.173 kb on + strand, within Rv1965 at 2209.174 kb on - strand, within Rv1965 at 2209.871 kb on + strand, within Rv1966 at 2209.975 kb on + strand, within Rv1966 at 2209.975 kb on + strand, within Rv1966 at 2209.976 kb on - strand, within Rv1966 at 2210.185 kb on + strand, within Rv1966 at 2210.186 kb on - strand, within Rv1966 at 2210.198 kb on - strand, within Rv1966 at 2210.246 kb on - strand, within Rv1966 at 2210.318 kb on - strand, within Rv1966 at 2210.504 kb on - strand at 2210.653 kb on + strand at 2210.654 kb on - strand at 2210.721 kb on + strand, within Rv1967 at 2210.722 kb on - strand, within Rv1967 at 2210.724 kb on + strand, within Rv1967 at 2210.724 kb on + strand, within Rv1967 at 2210.725 kb on - strand, within Rv1967 at 2210.725 kb on - strand, within Rv1967 at 2211.272 kb on - strand, within Rv1967 at 2211.447 kb on + strand, within Rv1967 at 2211.447 kb on + strand, within Rv1967 at 2211.447 kb on + strand, within Rv1967 at 2211.448 kb on - strand, within Rv1967 at 2211.483 kb on + strand, within Rv1967 at 2211.483 kb on + strand, within Rv1967 at 2211.511 kb on - strand, within Rv1967 at 2211.511 kb on - strand, within Rv1967 at 2211.531 kb on + strand at 2211.583 kb on - strand at 2211.583 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Meropenem 9.6 ug/mL remove 2,208,361 - Rv1964 0.83 -0.0 2,208,363 - Rv1964 0.83 -0.0 2,208,363 - Rv1964 0.83 -0.1 2,208,363 - Rv1964 0.83 +0.1 2,208,363 - Rv1964 0.83 -1.2 2,208,741 + Rv1965 0.29 -0.2 2,208,864 - Rv1965 0.44 +0.2 2,208,942 + Rv1965 0.53 -0.2 2,209,017 + Rv1965 0.62 -0.3 2,209,018 - Rv1965 0.63 -0.3 2,209,018 - Rv1965 0.63 +2.0 2,209,050 + Rv1965 0.67 -1.7 2,209,050 + Rv1965 0.67 -0.2 2,209,051 - Rv1965 0.67 -0.2 2,209,051 - Rv1965 0.67 -0.3 2,209,051 - Rv1965 0.67 -2.2 2,209,051 - Rv1965 0.67 -0.6 2,209,071 + Rv1965 0.69 +0.1 2,209,071 + Rv1965 0.69 -0.8 2,209,072 - Rv1965 0.69 +0.6 2,209,081 - Rv1965 0.70 +0.2 2,209,081 - Rv1965 0.70 +0.1 2,209,170 + Rv1965 0.81 +1.8 2,209,170 + Rv1965 0.81 -0.2 2,209,171 - Rv1965 0.81 +1.8 2,209,171 - Rv1965 0.81 +1.8 2,209,173 + Rv1965 0.82 +0.8 2,209,174 - Rv1965 0.82 +1.0 2,209,871 + Rv1966 0.43 +0.0 2,209,975 + Rv1966 0.51 -0.3 2,209,975 + Rv1966 0.51 -0.7 2,209,976 - Rv1966 0.51 -0.6 2,210,185 + Rv1966 0.67 -0.2 2,210,186 - Rv1966 0.67 +0.4 2,210,198 - Rv1966 0.68 -0.2 2,210,246 - Rv1966 0.72 -0.7 2,210,318 - Rv1966 0.78 -1.0 2,210,504 - -0.1 2,210,653 + -0.8 2,210,654 - -0.1 2,210,721 + Rv1967 0.12 -0.6 2,210,722 - Rv1967 0.12 +0.2 2,210,724 + Rv1967 0.12 -1.2 2,210,724 + Rv1967 0.12 -0.4 2,210,725 - Rv1967 0.12 -1.0 2,210,725 - Rv1967 0.12 -0.1 2,211,272 - Rv1967 0.65 +0.4 2,211,447 + Rv1967 0.82 -0.9 2,211,447 + Rv1967 0.82 -0.4 2,211,447 + Rv1967 0.82 -0.5 2,211,448 - Rv1967 0.82 -0.4 2,211,483 + Rv1967 0.86 +1.9 2,211,483 + Rv1967 0.86 -1.8 2,211,511 - Rv1967 0.88 -0.3 2,211,511 - Rv1967 0.88 -0.7 2,211,531 + -0.3 2,211,583 - -0.4 2,211,583 - +0.1
Or see this region's nucleotide sequence