Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1932

Experiment: 7H9 with Meropenem 9.6 ug/mL

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv1930c and Rv1931c are separated by 17 nucleotidesRv1931c and Rv1932 are separated by 132 nucleotidesRv1932 and Rv1933c overlap by 4 nucleotides Rv1930c: Rv1930c - Conserved hypothetical protein, at 2,181,918 to 2,182,442 Rv1930c Rv1931c: Rv1931c - Probable transcriptional regulatory protein, at 2,182,460 to 2,183,239 Rv1931c Rv1932: Rv1932 - Probable thiol peroxidase Tpx, at 2,183,372 to 2,183,869 Rv1932 Rv1933c: Rv1933c - Probable acyl-CoA dehydrogenase FadE18, at 2,183,866 to 2,184,957 Rv1933c Position (kb) 2183 2184Strain fitness (log2 ratio) -2 -1 0 1 2at 2182.382 kb on - strand, within Rv1930cat 2182.418 kb on - strandat 2182.494 kb on - strandat 2182.838 kb on + strand, within Rv1931cat 2182.838 kb on + strand, within Rv1931cat 2183.308 kb on + strandat 2183.382 kb on + strandat 2183.421 kb on + strandat 2183.837 kb on + strandat 2183.960 kb on + strandat 2183.960 kb on + strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Meropenem 9.6 ug/mL
remove
2,182,382 - Rv1930c 0.88 -1.4
2,182,418 - -1.8
2,182,494 - -1.4
2,182,838 + Rv1931c 0.48 +0.1
2,182,838 + Rv1931c 0.48 -0.3
2,183,308 + +1.8
2,183,382 + -0.6
2,183,421 + +2.3
2,183,837 + +2.5
2,183,960 + -1.9
2,183,960 + -0.4

Or see this region's nucleotide sequence