Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1927

Experiment: 7H9 with Meropenem 9.6 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Meropenem 9.6 ug/mL
2,178,680	+		Rv1925	0.86	-0.7
2,178,680	+		Rv1925	0.86	-2.3
2,178,680	+		Rv1925	0.86	-0.2
2,178,681	-		Rv1925	0.86	-1.1
2,178,684	+		Rv1925	0.86	+0.6
2,178,684	+		Rv1925	0.86	+0.2
2,178,947	+				-0.3
2,178,947	+				-1.0
2,178,947	+				-1.5
2,178,947	+				+0.8
2,178,948	-				+0.1
2,178,948	-				-0.0
2,179,037	-		Rv1926c	0.17	+0.3
2,179,070	+		Rv1926c	0.24	-0.4
2,179,120	+		Rv1926c	0.34	-2.4
2,179,315	-		Rv1926c	0.75	+1.8
2,179,444	+				+0.8
2,179,444	+				-0.1
2,179,453	+				-0.2
2,179,453	+				+0.0
2,179,454	-				-0.9
2,179,454	-				+0.2
2,179,502	+				+0.4
2,179,503	-				+0.1
2,179,503	-				+0.4
2,179,684	-				-0.0
2,179,887	-		Rv1927	0.28	-1.3
2,179,887	-		Rv1927	0.28	-1.2
2,179,887	-		Rv1927	0.28	-0.3
2,179,985	+		Rv1927	0.40	+1.3
2,180,071	-		Rv1927	0.51	-0.2
2,180,088	-		Rv1927	0.54	+0.1
2,180,131	+		Rv1927	0.59	-0.4
2,180,131	+		Rv1927	0.59	-0.8
2,180,179	-		Rv1927	0.65	+0.2
2,180,254	+		Rv1927	0.75	-1.6
2,180,254	+		Rv1927	0.75	-0.1
2,180,255	-		Rv1927	0.75	-0.8
2,180,296	+		Rv1927	0.80	-0.0
2,180,296	+		Rv1927	0.80	-0.1
2,180,464	-				-0.3
2,180,497	+				+0.5
2,180,500	-				+1.2
2,180,524	-				+0.6
2,180,599	-		Rv1928c	0.19	+0.7
2,180,608	-		Rv1928c	0.21	+0.5
2,181,127	-		Rv1928c	0.88	-0.2
2,181,127	-		Rv1928c	0.88	-0.4
2,181,354	-		Rv1929c	0.14	-0.4