Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1749c

Experiment: 7H9 with Meropenem 9.6 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Meropenem 9.6 ug/mL
1,976,668	-				-0.0
1,976,668	-				+1.2
1,976,721	+		Rv1748	0.17	+0.8
1,976,721	+		Rv1748	0.17	+1.8
1,976,721	+		Rv1748	0.17	+0.9
1,976,721	+		Rv1748	0.17	+0.1
1,976,721	+		Rv1748	0.17	-0.5
1,976,721	+		Rv1748	0.17	-0.3
1,976,721	+		Rv1748	0.17	-0.1
1,976,722	-		Rv1748	0.17	-1.1
1,976,722	-		Rv1748	0.17	+0.0
1,976,722	-		Rv1748	0.17	-0.1
1,976,722	-		Rv1748	0.17	-0.2
1,976,722	-		Rv1748	0.17	+0.3
1,976,722	-		Rv1748	0.17	+0.4
1,976,723	+		Rv1748	0.17	+0.3
1,976,723	+		Rv1748	0.17	-0.2
1,976,723	+		Rv1748	0.17	+0.6
1,976,723	+		Rv1748	0.17	-0.1
1,976,724	-		Rv1748	0.17	-0.3
1,976,724	-		Rv1748	0.17	-0.1
1,976,724	-		Rv1748	0.17	+0.3
1,976,724	-		Rv1748	0.17	+0.2
1,976,764	-		Rv1748	0.22	-0.1
1,976,991	+		Rv1748	0.53	-0.1
1,976,992	-		Rv1748	0.54	+0.2
1,976,992	-		Rv1748	0.54	+0.2
1,977,080	+		Rv1748	0.66	+0.3
1,977,081	-		Rv1748	0.66	+1.0
1,977,081	-		Rv1748	0.66	+0.5
1,977,234	-		Rv1748	0.87	-1.1
1,977,284	-				+0.0
1,977,329	+				+0.5
1,977,329	+				+0.1
1,977,380	+				+0.1
1,977,403	+		Rv1749c	0.13	+2.3
1,977,403	+		Rv1749c	0.13	-0.2
1,977,441	-		Rv1749c	0.20	+0.3
1,977,441	-		Rv1749c	0.20	-0.4
1,977,441	-		Rv1749c	0.20	+1.8
1,977,470	+		Rv1749c	0.25	-0.6
1,977,471	-		Rv1749c	0.26	+0.8
1,977,474	-		Rv1749c	0.26	-0.0
1,977,474	-		Rv1749c	0.26	-0.0
1,977,501	-		Rv1749c	0.31	-0.1
1,977,501	-		Rv1749c	0.31	+0.2
1,977,555	-		Rv1749c	0.41	-0.4
1,977,630	+		Rv1749c	0.54	+0.2
1,977,633	-		Rv1749c	0.55	-0.0
1,977,674	+		Rv1749c	0.62	+1.1
1,977,674	+		Rv1749c	0.62	-1.1
1,977,729	+		Rv1749c	0.72	+0.1
1,977,730	-		Rv1749c	0.72	-0.9
1,977,730	-		Rv1749c	0.72	+0.2
1,977,787	+		Rv1749c	0.82	+0.3
1,977,835	+				+0.7
1,977,841	+				-1.7
1,977,965	+				-0.7
1,977,972	+				+0.6
1,977,973	-				-0.1
1,978,003	+				-2.1
1,978,003	+				-0.7
1,978,133	-		Rv1750c	0.10	+0.2
1,978,156	-		Rv1750c	0.12	+1.0
1,978,426	+		Rv1750c	0.29	-0.8
1,978,471	+		Rv1750c	0.31	-0.0
1,978,471	+		Rv1750c	0.31	-1.1
1,978,471	+		Rv1750c	0.31	+0.2
1,978,471	+		Rv1750c	0.31	+0.1
1,978,816	+		Rv1750c	0.53	+0.0
1,978,837	+		Rv1750c	0.54	-0.7
1,978,837	+		Rv1750c	0.54	-1.1
1,978,837	+		Rv1750c	0.54	-1.5
1,978,838	-		Rv1750c	0.54	-1.0
1,978,838	-		Rv1750c	0.54	-0.0
1,978,838	-		Rv1750c	0.54	-0.2
1,978,844	+		Rv1750c	0.55	+0.3
1,978,845	-		Rv1750c	0.55	-0.6