Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1557

Experiment: 7H9 with Meropenem 9.6 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Meropenem 9.6 ug/mL
1,760,923	+				-0.2
1,760,923	+				-0.5
1,760,924	-				+0.1
1,760,927	+				-0.6
1,760,927	+				+0.1
1,760,928	-				-0.3
1,760,996	+				-0.7
1,760,997	-				+0.4
1,761,001	+				+0.1
1,761,085	+		Rv1556	0.14	+0.1
1,761,085	+		Rv1556	0.14	-1.0
1,761,086	-		Rv1556	0.15	+0.3
1,761,118	+		Rv1556	0.20	-0.5
1,761,418	-		Rv1556	0.69	-0.0
1,761,574	+				+0.2
1,761,575	-				-0.3
1,761,575	-				-0.3
1,761,688	-				+0.1
1,761,856	+				-0.5
1,761,954	-		Rv1557	0.18	-0.8
1,761,958	-		Rv1557	0.18	-0.1
1,761,979	-		Rv1557	0.20	-0.4
1,762,059	+		Rv1557	0.26	-0.1
1,762,059	+		Rv1557	0.26	-0.6
1,762,060	-		Rv1557	0.26	-1.1
1,762,130	+		Rv1557	0.32	+0.3
1,762,261	-		Rv1557	0.43	-0.2
1,762,261	-		Rv1557	0.43	+0.8
1,762,311	+		Rv1557	0.47	-0.2
1,762,312	-		Rv1557	0.48	+1.8
1,762,312	-		Rv1557	0.48	+1.4
1,762,540	-		Rv1557	0.67	-0.2
1,762,664	+		Rv1557	0.77	-0.3
1,762,664	+		Rv1557	0.77	-0.1
1,762,664	+		Rv1557	0.77	+0.2
1,762,665	-		Rv1557	0.77	+0.9
1,762,665	-		Rv1557	0.77	+0.9
1,762,665	-		Rv1557	0.77	-0.1
1,762,965	+				+0.1
1,762,965	+				+1.8
1,762,965	+				+0.3
1,762,965	+				-0.1
1,763,010	+		Rv1558	0.14	+1.2
1,763,010	+		Rv1558	0.14	-0.9
1,763,010	+		Rv1558	0.14	-0.2
1,763,011	-		Rv1558	0.14	+0.1
1,763,011	-		Rv1558	0.14	+0.7
1,763,011	-		Rv1558	0.14	-1.0
1,763,011	-		Rv1558	0.14	-0.5
1,763,011	-		Rv1558	0.14	-0.3
1,763,011	-		Rv1558	0.14	-1.5
1,763,012	+		Rv1558	0.15	-1.0
1,763,013	-		Rv1558	0.15	+0.4
1,763,013	-		Rv1558	0.15	+3.0
1,763,102	+		Rv1558	0.35	+1.9
1,763,103	-		Rv1558	0.35	+0.5
1,763,140	-		Rv1558	0.43	+0.3
1,763,320	-		Rv1558	0.83	-0.7
1,763,329	-		Rv1558	0.85	-0.2
1,763,329	-		Rv1558	0.85	+1.3