Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1425

Experiment: 7H9 with Meropenem 9.6 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Meropenem 9.6 ug/mL
1,598,895	-				+1.0
1,599,179	+		Rv1424c	0.38	+0.2
1,599,210	-		Rv1424c	0.42	+0.2
1,599,213	-		Rv1424c	0.42	-0.1
1,599,213	-		Rv1424c	0.42	-0.5
1,599,356	+		Rv1424c	0.61	-0.1
1,599,357	-		Rv1424c	0.61	+0.9
1,599,423	-		Rv1424c	0.70	+0.0
1,599,440	+		Rv1424c	0.72	-0.3
1,599,550	-		Rv1424c	0.86	+0.1
1,599,646	+				-0.8
1,599,655	-				-0.8
1,599,655	-				-0.3
1,599,655	-				+0.6
1,599,717	+				-0.4
1,599,717	+				-1.0
1,599,718	-				-0.4
1,599,767	-				-0.7
1,599,767	-				+0.0
1,599,980	-		Rv1425	0.23	+0.3
1,599,980	-		Rv1425	0.23	-0.8
1,600,481	-		Rv1425	0.60	+0.1
1,600,481	-		Rv1425	0.60	+0.1
1,600,612	-		Rv1425	0.69	-0.1
1,600,757	-		Rv1425	0.80	+0.9
1,600,837	+		Rv1425	0.85	-0.2
1,600,837	+		Rv1425	0.85	-0.2
1,600,837	+		Rv1425	0.85	+0.6
1,600,837	+		Rv1425	0.85	-0.3
1,600,838	-		Rv1425	0.86	+0.6
1,600,838	-		Rv1425	0.86	-1.5
1,600,838	-		Rv1425	0.86	-0.9
1,600,838	-		Rv1425	0.86	+0.5
1,600,839	+		Rv1425	0.86	-0.7
1,600,839	+		Rv1425	0.86	-0.1
1,600,839	+		Rv1425	0.86	+0.1
1,600,840	-		Rv1425	0.86	+1.5
1,600,930	+				+1.8
1,601,035	+				+0.5
1,601,041	+				-0.3
1,601,041	+				-0.4
1,601,041	+				-0.1
1,601,051	-				+0.4
1,601,052	+				+0.3
1,601,053	-				+0.6
1,601,060	+				+1.1
1,601,084	+				+0.8
1,601,672	+		Rv1426c	0.49	-1.4
1,601,673	-		Rv1426c	0.49	-0.3
1,601,673	-		Rv1426c	0.49	-0.4
1,601,858	+		Rv1426c	0.63	-0.5
1,601,858	+		Rv1426c	0.63	-0.7
1,601,934	+		Rv1426c	0.69	-0.0
1,601,970	+		Rv1426c	0.72	+0.1
1,601,975	+		Rv1426c	0.73	-0.6