Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1385

Experiment: 7H9 with Meropenem 9.6 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Meropenem 9.6 ug/mL
1,561,373	-				-0.2
1,561,414	-				-1.3
1,561,414	-				-1.0
1,561,565	+		Rv1386	0.33	-1.2
1,561,637	+		Rv1386	0.56	+2.8
1,561,719	+		Rv1386	0.83	+0.1
1,561,719	+		Rv1386	0.83	-0.8
1,561,719	+		Rv1386	0.83	-0.4
1,561,719	+		Rv1386	0.83	-0.3
1,561,719	+		Rv1386	0.83	-0.2
1,561,727	+		Rv1386	0.85	-0.4
1,561,752	+				-0.6
1,561,752	+				-1.4
1,561,752	+				-0.4
1,561,752	+				-1.9
1,561,753	-				-0.0
1,561,769	-				-1.3
1,561,823	+				+0.1
1,561,886	+				-0.7
1,561,887	-				-1.2
1,561,979	+		Rv1387	0.13	+0.1
1,561,979	+		Rv1387	0.13	-0.3
1,561,979	+		Rv1387	0.13	-2.7
1,561,980	-		Rv1387	0.13	-1.4
1,561,980	-		Rv1387	0.13	-1.2
1,562,063	+		Rv1387	0.18	+1.0
1,562,148	+		Rv1387	0.23	-0.6
1,562,192	+		Rv1387	0.26	+0.8
1,562,192	+		Rv1387	0.26	-0.2
1,562,193	-		Rv1387	0.26	-0.8
1,562,193	-		Rv1387	0.26	-0.1
1,562,193	-		Rv1387	0.26	-0.5
1,562,234	+		Rv1387	0.29	+0.6
1,562,234	+		Rv1387	0.29	-0.3
1,562,235	-		Rv1387	0.29	-0.8
1,562,235	-		Rv1387	0.29	-0.2
1,562,235	-		Rv1387	0.29	-1.0
1,562,235	-		Rv1387	0.29	-1.1