Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1278

Experiment: 7H9 with Meropenem 9.6 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Meropenem 9.6 ug/mL
1,426,414	+		Rv1277	0.20	-0.7
1,426,459	+		Rv1277	0.24	+0.6
1,426,506	+		Rv1277	0.27	-0.3
1,426,840	-		Rv1277	0.54	-0.5
1,426,868	+		Rv1277	0.56	-0.2
1,426,960	+		Rv1277	0.63	-0.7
1,427,039	+		Rv1277	0.70	-0.7
1,427,255	-		Rv1277	0.87	-0.5
1,427,562	-				-1.1
1,427,954	+		Rv1278	0.21	-0.7
1,428,133	-		Rv1278	0.27	-2.4
1,428,133	-		Rv1278	0.27	+0.8
1,428,591	+		Rv1278	0.45	-1.0
1,428,591	+		Rv1278	0.45	+0.5
1,428,591	+		Rv1278	0.45	-0.4
1,428,592	-		Rv1278	0.45	-0.3
1,429,206	+		Rv1278	0.68	-0.8
1,429,778	+		Rv1278	0.90	-0.7
1,430,034	+				-0.3
1,430,034	+				+0.2
1,430,035	-				+0.4
1,430,081	-				-0.1
1,430,081	-				-1.2
1,430,081	-				-1.9
1,430,081	-				+0.3
1,430,248	+		Rv1279	0.12	+0.4
1,431,026	-		Rv1279	0.61	-0.0
1,431,029	+		Rv1279	0.61	+0.1
1,431,030	-		Rv1279	0.61	-0.2
1,431,030	-		Rv1279	0.61	+0.0
1,431,030	-		Rv1279	0.61	-0.6